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儿科人群胃肠道疾病的发病机制、诊断、饮食管理和预防。

Pathogenesis, diagnosis, dietary management, and prevention of gastrointestinal disorders in the paediatric population.

机构信息

Pediatric Respiratory and Cystic Fibrosis Unit, Department of Clinical and Experimental Medicine, San Marco Hospital, University of Catania, Via Santa Sofia 78, 95123, Catania, Italy.

Pediatric Unit, Department of Human and Pediatric Pathology "Gaetano Barresi", AOUP G. Martino, University of Messina, Via Consolare Valeria, 1, 98124, Messina, Italy.

出版信息

Ital J Pediatr. 2022 Sep 11;48(1):172. doi: 10.1186/s13052-022-01366-8.

DOI:10.1186/s13052-022-01366-8
PMID:36089576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9465927/
Abstract

Nutrition has a central role in child growth with long-term effects, and nutrition management in gastrointestinal disorders has great importance for child health and disease outcomes. Breast milk is the first choice for infant nutrition. When it is not available, special milk formulas are adopted in specific conditions, as a medical treatment. Moving from the strong guidelines, recommendations and the new possibilities of special diet treatment, this review will analyse the current diet treatment in different gastrointestinal disorders, including food allergy, cystic fibrosis, inflammatory bowel diseases, short-bowel syndrome, gastroesophageal reflux, and eosinophilic esophagitis. The review also aimed at understanding the role of diet and its effects on these diseases. The growth monitoring can prevent malnutrition and improve disease outcomes, particularly in children, and an appropriate dietary management targeted to specific disorders is the best therapeutic choice alone or in combination with pharmacological therapy.

摘要

营养在儿童生长中起着核心作用,具有长期影响,胃肠道疾病的营养管理对儿童健康和疾病结局非常重要。母乳是婴儿营养的首选。当无法母乳喂养时,在特定情况下会采用特殊的配方奶,作为一种医疗手段。本综述从强有力的指南、建议和特殊饮食治疗的新可能性出发,分析了不同胃肠道疾病(包括食物过敏、囊性纤维化、炎症性肠病、短肠综合征、胃食管反流和嗜酸性食管炎)中的当前饮食治疗方法。本综述还旨在了解饮食的作用及其对这些疾病的影响。生长监测可以预防营养不良,改善疾病结局,特别是在儿童中,针对特定疾病的适当饮食管理是最佳的治疗选择,单独或联合药物治疗均可。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/561d/9465927/64e5baafae65/13052_2022_1366_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/561d/9465927/eae6fec98649/13052_2022_1366_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/561d/9465927/64e5baafae65/13052_2022_1366_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/561d/9465927/eae6fec98649/13052_2022_1366_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/561d/9465927/64e5baafae65/13052_2022_1366_Fig2_HTML.jpg

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本文引用的文献

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Front Pediatr. 2021 Oct 22;9:727127. doi: 10.3389/fped.2021.727127. eCollection 2021.
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The Impact of Formula Choice for the Management of Pediatric Cow's Milk Allergy on the Occurrence of Other Allergic Manifestations: The Atopic March Cohort Study.配方选择对小儿牛奶过敏管理中其他过敏表现发生的影响:特应性进行曲队列研究。
J Pediatr. 2021 May;232:183-191.e3. doi: 10.1016/j.jpeds.2021.01.059. Epub 2021 Jan 29.
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Focus on gastroesophageal reflux disease in patients with cystic fibrosis.
关注囊性纤维化患者的胃食管反流病。
World J Gastroenterol. 2020 Nov 7;26(41):6322-6334. doi: 10.3748/wjg.v26.i41.6322.
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Allergy Modulation by N-3 Long Chain Polyunsaturated Fatty Acids and Fat Soluble Nutrients of the Mediterranean Diet.地中海饮食中的n-3长链多不饱和脂肪酸和脂溶性营养素对过敏的调节作用。
Front Pharmacol. 2020 Aug 21;11:1244. doi: 10.3389/fphar.2020.01244. eCollection 2020.
6
Improved residual fat malabsorption and growth in children with cystic fibrosis treated with a novel oral structured lipid supplement: A randomized controlled trial.新型口服结构化脂肪补充剂治疗囊性纤维化儿童的残余脂肪吸收不良和生长改善:一项随机对照试验。
PLoS One. 2020 May 8;15(5):e0232685. doi: 10.1371/journal.pone.0232685. eCollection 2020.
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Effects of low glycemic index/high-fat, high-calorie diet on glycemic control and lipid profiles of children and adolescence with cystic fibrosis: A randomized double-blind controlled clinical trial.低血糖指数/高脂肪、高热量饮食对囊性纤维化儿童及青少年血糖控制和血脂水平的影响:一项随机双盲对照临床试验
Diabetes Metab Syndr. 2020 Mar-Apr;14(2):87-92. doi: 10.1016/j.dsx.2019.12.010. Epub 2020 Jan 8.
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Understanding short bowel syndrome: Current status and future perspectives.理解短肠综合征:现状与未来展望。
Dig Liver Dis. 2020 Mar;52(3):253-261. doi: 10.1016/j.dld.2019.11.013. Epub 2019 Dec 28.
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Histopathology of inflammatory bowel disease - Position statement of the Pathologists of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD) and Italian Group of Gastrointestinal Pathologists (GIPAD-SIAPEC).炎症性肠病的组织病理学 - 意大利炎症性肠病研究组病理学家(IG-IBD)和意大利胃肠病学家病理学家组(GIPAD-SIAPEC)的立场声明。
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