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一名患有复杂肺部疾病的患者感染了 spp.:病例报告。 (注:原文中“spp.”表述不完整准确,可能影响对具体内容的理解)

Co-infection with spp. in a patient wit complex pulmonary disease: A case report.

作者信息

Tokita Nozomi, Urabe Naohisa, Sakamoto Susumu, Yamaguchi Asuka, Sekiguchi Ryo, Kishi Kazuma

机构信息

Department of Respiratory Medicine Toho University Omori Medical Center Tokyo Japan.

出版信息

Respirol Case Rep. 2022 Sep 7;10(10):e01036. doi: 10.1002/rcr2.1036. eCollection 2022 Oct.

Abstract

pulmonary disease (MAC-PD) is sometimes accompanied by co-infection with other pathogenic microorganisms such as and . However, co-infection with spp. has been rarely reported. We report on a patient diagnosed as having co-infection with after treatment for MAC-PD, which was successfully treated using trimethoprim-sulfamethoxazole (TMP-SMX). A 74-year-old woman with MAC-PD was admitted to our hospital to undergo re-examination for pathogenic microorganisms because chest computed tomography (CT) findings did not improve after treatment for MAC-PD. She underwent bronchoscopy and was detected from bronchoalveolar lavage fluid culture. Chest CT findings improved after 6 months of treatment using TMP-SMX. Co-infection with other pathogenic microorganisms should be considered when chest CT findings worsen after adequate treatment of MAC-PD. Chest CT findings of pulmonary disease in immunocompetent patients can mimic those of MAC-PD and should therefore be differentiated one from the other.

摘要

非结核分枝杆菌肺病(MAC-PD)有时会伴有与其他致病微生物如[具体微生物1]和[具体微生物2]的合并感染。然而,与[某种微生物]属的合并感染鲜有报道。我们报告了一例在接受MAC-PD治疗后被诊断为合并感染[某种微生物]的患者,该患者使用甲氧苄啶-磺胺甲恶唑(TMP-SMX)成功治愈。一名患有MAC-PD的74岁女性因MAC-PD治疗后胸部计算机断层扫描(CT)结果未改善而入院接受致病微生物复查。她接受了支气管镜检查,并从支气管肺泡灌洗液体培养中检测到[某种微生物]。使用TMP-SMX治疗6个月后胸部CT结果改善。在MAC-PD经过充分治疗后胸部CT结果恶化时,应考虑合并其他致病微生物感染。免疫功能正常患者的[某种肺病]的胸部CT表现可能与MAC-PD相似,因此应加以鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ba5/9452899/a1f693631bbf/RCR2-10-e01036-g001.jpg

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