Tokita Nozomi, Urabe Naohisa, Sakamoto Susumu, Yamaguchi Asuka, Sekiguchi Ryo, Kishi Kazuma
Department of Respiratory Medicine Toho University Omori Medical Center Tokyo Japan.
Respirol Case Rep. 2022 Sep 7;10(10):e01036. doi: 10.1002/rcr2.1036. eCollection 2022 Oct.
pulmonary disease (MAC-PD) is sometimes accompanied by co-infection with other pathogenic microorganisms such as and . However, co-infection with spp. has been rarely reported. We report on a patient diagnosed as having co-infection with after treatment for MAC-PD, which was successfully treated using trimethoprim-sulfamethoxazole (TMP-SMX). A 74-year-old woman with MAC-PD was admitted to our hospital to undergo re-examination for pathogenic microorganisms because chest computed tomography (CT) findings did not improve after treatment for MAC-PD. She underwent bronchoscopy and was detected from bronchoalveolar lavage fluid culture. Chest CT findings improved after 6 months of treatment using TMP-SMX. Co-infection with other pathogenic microorganisms should be considered when chest CT findings worsen after adequate treatment of MAC-PD. Chest CT findings of pulmonary disease in immunocompetent patients can mimic those of MAC-PD and should therefore be differentiated one from the other.
非结核分枝杆菌肺病（MAC-PD）有时会伴有与其他致病微生物如[具体微生物1]和[具体微生物2]的合并感染。然而，与[某种微生物]属的合并感染鲜有报道。我们报告了一例在接受MAC-PD治疗后被诊断为合并感染[某种微生物]的患者，该患者使用甲氧苄啶-磺胺甲恶唑（TMP-SMX）成功治愈。一名患有MAC-PD的74岁女性因MAC-PD治疗后胸部计算机断层扫描（CT）结果未改善而入院接受致病微生物复查。她接受了支气管镜检查，并从支气管肺泡灌洗液体培养中检测到[某种微生物]。使用TMP-SMX治疗6个月后胸部CT结果改善。在MAC-PD经过充分治疗后胸部CT结果恶化时，应考虑合并其他致病微生物感染。免疫功能正常患者的[某种肺病]的胸部CT表现可能与MAC-PD相似，因此应加以鉴别。
