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本文引用的文献

1
Co-infection with spp. in a patient wit complex pulmonary disease: A case report.一名患有复杂肺部疾病的患者感染了 spp.:病例报告。 (注:原文中“spp.”表述不完整准确,可能影响对具体内容的理解)
Respirol Case Rep. 2022 Sep 7;10(10):e01036. doi: 10.1002/rcr2.1036. eCollection 2022 Oct.
2
Pneumococcal Pneumonia Co-infection with Mycobacterium avium and Nocardia cyriacigeorgica in an Immunocompetent Patient.免疫功能正常患者中肺炎球菌肺炎合并鸟分枝杆菌和赛氏诺卡菌感染
Intern Med. 2022 Apr 15;61(8):1285-1290. doi: 10.2169/internalmedicine.6895-20. Epub 2021 Oct 19.
3
Epidemiology of nontuberculous mycobacterial pulmonary disease in Europe and Japan by Delphi estimation.德尔菲法评估欧洲和日本的非结核分枝杆菌肺病的流行病学。
Respir Med. 2020 Nov;173:106164. doi: 10.1016/j.rmed.2020.106164. Epub 2020 Sep 21.
4
Interrelational changes in the epidemiology and clinical features of nontuberculous mycobacterial pulmonary disease and tuberculosis in a referral hospital in Japan.日本一家转诊医院中,非结核分枝杆菌肺病和结核病的流行病学和临床特征的相互关系变化。
Respir Med. 2019 Jun;152:74-80. doi: 10.1016/j.rmed.2019.05.001. Epub 2019 May 8.
5
Manifestations and outcomes of nocardia infections: Comparison of immunocompromised and nonimmunocompromised adult patients.诺卡菌感染的表现及结局:免疫功能低下与非免疫功能低下成年患者的比较
Medicine (Baltimore). 2018 Oct;97(40):e12436. doi: 10.1097/MD.0000000000012436.
6
Pulmonary Nocardiosis: A Clinical Analysis of 30 Cases.肺诺卡菌病:30例临床分析
Intern Med. 2017;56(12):1485-1490. doi: 10.2169/internalmedicine.56.8163. Epub 2017 Jun 15.
7
Increasing Nocardia Incidence Associated with Bronchiectasis at a Tertiary Care Center.在一家三级医疗中心,与支气管扩张相关的诺卡菌发病率上升。
Ann Am Thorac Soc. 2017 Mar;14(3):347-354. doi: 10.1513/AnnalsATS.201611-907OC.
8
Clinical characteristics of pulmonary nocardiosis in immunocompetent patients.免疫功能正常患者肺诺卡菌病的临床特征
J Infect Chemother. 2016 Nov;22(11):738-743. doi: 10.1016/j.jiac.2016.08.004. Epub 2016 Sep 5.
9
Pulmonary nocardiosis caused by Nocardia cyriacigeorgica in patients with Mycobacterium avium complex lung disease: two case reports.鸟分枝杆菌复合群肺病患者中由乔治西里亚星诺卡菌引起的肺诺卡菌病:两例报告
BMC Infect Dis. 2014 Dec 10;14:684. doi: 10.1186/s12879-014-0684-z.
10
Pulmonary nocardiosis: a clinical analysis of 59 cases.肺诺卡菌病:59例临床分析
Respir Investig. 2014 May;52(3):160-6. doi: 10.1016/j.resinv.2013.09.004. Epub 2013 Nov 7.

免疫功能正常患者结节性支气管扩张性复合肺病后继发肺诺卡菌病。

Pulmonary nocardiosis following nodular bronchiectatic complex pulmonary disease in an immunocompetent patient.

机构信息

Department of Respiratory Medicine, NHO Tenryu Hospital, Hamamatsu, Japan

Department of Respiratory Medicine, NHO Tenryu Hospital, Hamamatsu, Japan.

出版信息

BMJ Case Rep. 2023 Nov 16;16(11):e256007. doi: 10.1136/bcr-2023-256007.

DOI:10.1136/bcr-2023-256007
PMID:37973540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10660431/
Abstract

A woman in her 70s with a history of nodular bronchiectatic complex pulmonary disease (MAC-PD) presented with an exacerbated productive cough and worsening findings on chest imaging. Although repeated sputum culture tests were negative for acid-fast bacilli and only revealed normal respiratory flora, a bronchoscopy identified sp. Consequently, she was diagnosed with pulmonary nocardiosis and was successfully treated with levofloxacin. It is known that pulmonary nocardiosis can manifest in immunocompetent individuals with bronchiectasis. For cases of refractory nodular bronchiectatic MAC-PD, it is vital to consider bronchoscopy to identify potential co-infections, such as .

摘要

一位 70 多岁的女性,患有结节性支气管扩张型复杂肺部疾病(MAC-PD),出现咳嗽加剧和胸部影像学检查结果恶化。尽管反复的痰培养检测均为抗酸杆菌阴性,仅显示正常的呼吸道菌群,但支气管镜检查发现了 。因此,她被诊断为肺部奴卡菌病,并成功地接受左氧氟沙星治疗。已知肺部奴卡菌病可发生在支气管扩张的免疫功能正常的个体中。对于难治性结节性支气管扩张型 MAC-PD 病例,重要的是要考虑支气管镜检查以识别潜在的合并感染,如 。