Schwab Roxana, Droste Annika, Stewen Kathrin, Elger Tania, Theis Susanne, Heimes Anne-Sophie, Peters Katharina, Schmidt Marcus, Brenner Walburgis, Hasenburg Annette
Department of Obstetrics and Gynecology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, 55131, Germany.
Int J Gen Med. 2022 Sep 5;15:7039-7052. doi: 10.2147/IJGM.S373191. eCollection 2022.
The COVID-19 pandemic has affected individuals' and society's physical and psychological well-being. The study was conducted in order to assess the predictors for health-related worries during the COVID-19 pandemic in vulnerable populations.
A cross-sectional web-based survey of women who had a higher risk of developing breast cancer (BC) or ovarian cancer (OC) was conducted, regardless of whether they had experienced an active malignant disease during the pandemic. A self-reported questionnaire was designed for this study to assess health-related worries. The PHQ-4 questionnaire was used to evaluate mental health, and the Brief Resilience Scale (BRS) questionnaire was employed to investigate resilience.
History of BC or OC was recognized as an independent significant risk factor for worries regarding being more susceptible to a more severe course of COVID-19 disease (OR 3.593; 95% CI 1.030-12.536; p = 0.045). High scores in the BRS questionnaire were negatively correlated with health-related worries, such as an increased risk for occurrence of BC or OC (OR 0.332; 95% CI 0.118-0.933; p = 0.37) or worsening of oncological outcome as a result of an infection with the SARS-CoV-2 virus (OR 0.330; 95% I 0.114-0.956; p = 0.041).
The obtained findings determined resilience as an independent and potent protective parameter in terms of health-related concerns in women at high risk for BC and OC. The results may assist in identifying women at risk for health-related concerns during adverse life events, allowing healthcare providers to respond fast and according to the patients´ needs.
新冠疫情对个人和社会的身心健康产生了影响。本研究旨在评估弱势群体在新冠疫情期间与健康相关担忧的预测因素。
对有较高患乳腺癌（BC）或卵巢癌（OC）风险的女性进行了一项基于网络的横断面调查，无论她们在疫情期间是否经历过活动性恶性疾病。本研究设计了一份自我报告问卷来评估与健康相关的担忧。使用PHQ-4问卷评估心理健康，采用简易复原力量表（BRS）问卷调查复原力。
BC或OC病史被认为是担心更易患更严重新冠疾病过程的独立显著危险因素（比值比3.593；95%置信区间1.030 - 12.536；p = 0.045）。BRS问卷得分高与健康相关担忧呈负相关，如患BC或OC风险增加（比值比0.332；95%置信区间0.118 - 0.933；p = 0.37）或因感染SARS-CoV-2病毒导致肿瘤学结果恶化（比值比0.330；95%置信区间0.114 - 0.956；p = 0.041）。
研究结果确定复原力是BC和OC高危女性在健康相关问题方面的一个独立且有效的保护参数。这些结果可能有助于识别在不利生活事件期间有健康相关担忧风险的女性，使医疗服务提供者能够快速响应并根据患者需求提供服务。
