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黑人及拉丁裔黑人患者行透明晶状体切除术联合Hydrus支架植入术:一项1年的回顾性研究。

Clear Lensectomy with Hydrus Stent in Black and Afro-Latino Patients: A 1-Year Retrospective Study.

作者信息

Laroche Daniel, Oseni Jessinta, Nkrumah Gideon, Ng Chester

机构信息

Department of Ophthalmology, Icahn School of Medicine at Mount Sinai and New York Eye and Ear of Mount Sinai, New York, New York, USA.

Advanced Eyecare of New York, New York, New York, USA.

出版信息

J Ophthalmol. 2022 Aug 31;2022:8011745. doi: 10.1155/2022/8011745. eCollection 2022.

Abstract

PURPOSE

To determine the efficacy and safety of phacoemulsification, clear lensectomy, and the Hydrus microstent (Ivantis, Inc.) in Black and Afro-Latino glaucoma patients.

METHOD

This is a retrospective nonrandomized study of 134 Black and Afro-Latino patients who underwent clear lensectomy with Hydrus stent implant for the treatment of glaucoma. For comprehensive analysis, patients were divided into mild, moderate, and advanced glaucoma. The evaluated parameters were reductions in the number of medications, intraocular pressure (IOP), mean deviation on visual field test, and visual acuity.

RESULTS

A total of 134 patients with 1-year follow-up were evaluated. At 1 year, the average number of medications significantly decreased from 2.5 ± 1.4 preoperatively to 0.43 ± 1.04 ( < 0.001) and IOP decreased from 14.4 ± 3.9 to 13.8 ± 3.10 (=0.16). 110 (82.1%) patients were medication-free at 1 year ( = 57, 83.8% mild glaucoma;  = 37, 92.5% moderate glaucoma;  = 16, 61.5% advanced glaucoma). There was stabilization of mean deviation on the visual field test (baseline, -8.28; 1 year, -8.28; =1). The most reported adverse effects were transient IOP spike and hyphema ( = 7, 5.2%;  = 3, 2.2%, respectively); both events were self-resolving. No decline in vision or sight-threatening complications were reported at 1 year, and no additional surgeries were required.

CONCLUSION

This 1-year retrospective study demonstrated the efficacy and safety of clear lensectomy and Hydrus stent implantation in decreasing medication burden while maintaining lower IOP in Black and Afro-Latino glaucoma patients.

摘要

目的

确定超声乳化白内障吸除术、透明晶状体摘除术以及Hydrus微支架(Ivantis公司)在黑人及拉丁裔青光眼患者中的疗效和安全性。

方法

这是一项对134例接受透明晶状体摘除联合Hydrus支架植入术治疗青光眼的黑人及拉丁裔患者进行的回顾性非随机研究。为进行全面分析,将患者分为轻度、中度和重度青光眼。评估参数包括药物使用数量减少情况、眼压(IOP)、视野测试的平均偏差和视力。

结果

共评估了134例进行了1年随访的患者。1年后,药物平均使用数量从术前的2.5±1.4显著降至0.43±1.04(<0.001),眼压从14.4±3.9降至13.8±3.10(=0.16)。110例(82.1%)患者在1年后无需使用药物(轻度青光眼患者57例,占83.8%;中度青光眼患者37例,占92.5%;重度青光眼患者16例,占61.5%)。视野测试的平均偏差保持稳定(基线时为-8.28;1年后为-8.28;=1)。最常报告的不良反应是短暂性眼压峰值和前房积血(分别为7例,占5.2%;3例,占2.2%);这两种情况均自行缓解。1年后未报告视力下降或威胁视力的并发症,也无需额外手术。

结论

这项为期1年的回顾性研究表明,透明晶状体摘除术和Hydrus支架植入术在减轻黑人及拉丁裔青光眼患者药物负担的同时维持较低眼压方面具有疗效和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d53/9453024/35fcafb3a30d/JOPH2022-8011745.001.jpg

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