Alipanah Hiva, Abdollahi Abbas, Firooziyan Samira, Zarenezhad Elham, Jafari Mojtaba, Osanloo Mahmoud
Department of Physiology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Department of Microbiology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.
Interdiscip Perspect Infect Dis. 2022 Aug 31;2022:1616149. doi: 10.1155/2022/1616149. eCollection 2022.
essential oil (EGEO) possesses many biological effects such as antibacterial, antifungal, and insecticide properties. In the current study, the chemical composition of EGEO was first investigated using GC-MS analysis. Then, a nanoemulsion and nanogel containing EGEO (EGEO-nanoemulsion and EGEO-nanogel) were prepared. After that, the successful loading of EGEO was confirmed using ATR-FTIR analysis. EGEO-nanoemulsion and EGEO-nanogel with LC values of 27 and 32 g/mL showed promising efficacies against larvae. Besides, the efficacy of EGEO-nanogel (IC 187 g/mL) was significantly more potent than EGEO-nanoemulsion (IC 3732 g/mL) against However, no significant difference was observed in the efficacy of EGEO-nanoemulsion and EGEO-nanogel against Natural components, straightforward preparation, and proper efficacy are some of the advantages of EGEO-nanogel; it could be considered for further consideration against other pathogens and mosquito larvae.
香根草精油（EGEO）具有许多生物效应，如抗菌、抗真菌和杀虫特性。在当前研究中，首先使用气相色谱-质谱联用（GC-MS）分析对EGEO的化学成分进行了研究。然后，制备了含有EGEO的纳米乳液和纳米凝胶（EGEO-纳米乳液和EGEO-纳米凝胶）。之后，使用衰减全反射傅里叶变换红外光谱（ATR-FTIR）分析确认了EGEO的成功负载。LC值为27和32 g/mL的EGEO-纳米乳液和EGEO-纳米凝胶对幼虫显示出有前景的效果。此外，EGEO-纳米凝胶（IC 187 g/mL）对[此处原文缺失具体对象]的效果明显比EGEO-纳米乳液（IC 3732 g/mL）更强。然而，EGEO-纳米乳液和EGEO-纳米凝胶对[此处原文缺失具体对象]的效果未观察到显著差异。天然成分、制备简单和效果良好是EGEO-纳米凝胶的一些优点；它可被考虑进一步用于对抗其他病原体和蚊子幼虫。
