Gijsen Anton Frans, De Bruijn Kirstin Marie Jeanne, Mastboom Walter
Department of Surgery Medisch Spectrum Twente Enschede The Netherlands.
Clin Case Rep. 2022 Sep 6;10(9):e6261. doi: 10.1002/ccr3.6261. eCollection 2022 Sep.
Thyroid tissue in cervical lymph nodes is an interesting and rare phenomenon that cannot be directly explained by embryology. Distinguishing malignant from benign thyroid tissue in cervical lymph nodes can be challenging but is essential for treatment and might have legal implications. Patients with incidentally found thyroid tissue in cervical lymph nodes during thyroid surgery were retrospectively identified. Clinical data and findings on pathology were retrospectively collected. Two patients with thyroid tissue in cervical lymph nodes were identified. Conventional pathology complemented with immunohistochemistry and molecular diagnostics showed the thyroid tissue in cervical lymph nodes to be benign. We show that benign thyroid tissue in cervical lymph nodes can be found in the absence or presence of a primary thyroid malignancy. A conservative approach is recommended if pathology shows benign thyroid tissue in cervical lymph nodes.
颈部淋巴结中的甲状腺组织是一种有趣且罕见的现象，胚胎学无法直接解释这一现象。区分颈部淋巴结中甲状腺组织的良恶性具有挑战性，但对于治疗至关重要，且可能具有法律意义。我们回顾性地确定了在甲状腺手术期间偶然发现颈部淋巴结中有甲状腺组织的患者。回顾性收集了临床数据和病理检查结果。确定了两名颈部淋巴结中有甲状腺组织的患者。常规病理学结合免疫组织化学和分子诊断显示颈部淋巴结中的甲状腺组织为良性。我们发现，无论是否存在原发性甲状腺恶性肿瘤，颈部淋巴结中均可发现良性甲状腺组织。如果病理显示颈部淋巴结中的甲状腺组织为良性，建议采取保守方法。
