精索静脉血中钠、钾和尿素浓度升高：精索静脉曲张睾丸功能障碍的另一个致病因素？

Raised sodium, potassium, and urea concentrations in spermatic venous blood: an additional causative factor in the testicular dysfunction of varicocele?

作者信息

Adamopoulos D A, Kontogeorgos L, Abrahamian-Michalakis A, Terzis T, Vassilopoulos P

出版信息

Fertil Steril. 1987 Aug;48(2):331-3. doi: 10.1016/s0015-0282(16)59368-6.

Abstract

The concentrations of Na, K, Cl, HCO3, LA, and urea, with calculation of the AG, as indirect indices of electrolyte balance and metabolic conditions prevailing in testicular environment, were determined in PB and SVB of 24 men with varicocele and 15 men with inguinal hernia. Significantly higher concentrations of Na, K, and urea were found in SVB as compared with PB values (P less than 0.001 for all) of patients with varicocele, but not in control subjects. The SVB concentrations of Na, K, and urea in varicocele patients were higher than SVB and PB concentrations of the control group (P less than 0.001 for all). It is concluded that urea, Na, and K concentrations are raised in SVB of patients with varicocele; this imbalance may be related, among other factors, to the pathogenesis of dyspermia in varicocele.

摘要

对24例精索静脉曲张患者和15例腹股沟疝患者的阴囊肉膜（PB）和精索静脉丛（SVB）进行检测，测定其中钠、钾、氯、碳酸氢根、乳酸和尿素的浓度，并计算阴离子间隙（AG），以此作为睾丸环境中电解质平衡和代谢状况的间接指标。精索静脉曲张患者的SVB中钠、钾和尿素的浓度显著高于PB值（均P<0.001），而对照组未出现此情况。精索静脉曲张患者的SVB中钠、钾和尿素的浓度高于对照组的SVB和PB浓度（均P<0.001）。研究得出结论，精索静脉曲张患者的SVB中尿素、钠和钾的浓度升高；这种失衡可能与精索静脉曲张患者精子异常的发病机制等多种因素有关。