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精索静脉血中钠、钾和尿素浓度升高:精索静脉曲张睾丸功能障碍的另一个致病因素?

Raised sodium, potassium, and urea concentrations in spermatic venous blood: an additional causative factor in the testicular dysfunction of varicocele?

作者信息

Adamopoulos D A, Kontogeorgos L, Abrahamian-Michalakis A, Terzis T, Vassilopoulos P

出版信息

Fertil Steril. 1987 Aug;48(2):331-3. doi: 10.1016/s0015-0282(16)59368-6.

DOI:10.1016/s0015-0282(16)59368-6
PMID:3609346
Abstract

The concentrations of Na, K, Cl, HCO3, LA, and urea, with calculation of the AG, as indirect indices of electrolyte balance and metabolic conditions prevailing in testicular environment, were determined in PB and SVB of 24 men with varicocele and 15 men with inguinal hernia. Significantly higher concentrations of Na, K, and urea were found in SVB as compared with PB values (P less than 0.001 for all) of patients with varicocele, but not in control subjects. The SVB concentrations of Na, K, and urea in varicocele patients were higher than SVB and PB concentrations of the control group (P less than 0.001 for all). It is concluded that urea, Na, and K concentrations are raised in SVB of patients with varicocele; this imbalance may be related, among other factors, to the pathogenesis of dyspermia in varicocele.

摘要

对24例精索静脉曲张患者和15例腹股沟疝患者的阴囊肉膜(PB)和精索静脉丛(SVB)进行检测,测定其中钠、钾、氯、碳酸氢根、乳酸和尿素的浓度,并计算阴离子间隙(AG),以此作为睾丸环境中电解质平衡和代谢状况的间接指标。精索静脉曲张患者的SVB中钠、钾和尿素的浓度显著高于PB值(均P<0.001),而对照组未出现此情况。精索静脉曲张患者的SVB中钠、钾和尿素的浓度高于对照组的SVB和PB浓度(均P<0.001)。研究得出结论,精索静脉曲张患者的SVB中尿素、钠和钾的浓度升高;这种失衡可能与精索静脉曲张患者精子异常的发病机制等多种因素有关。

相似文献

1
Raised sodium, potassium, and urea concentrations in spermatic venous blood: an additional causative factor in the testicular dysfunction of varicocele?精索静脉血中钠、钾和尿素浓度升高:精索静脉曲张睾丸功能障碍的另一个致病因素?
Fertil Steril. 1987 Aug;48(2):331-3. doi: 10.1016/s0015-0282(16)59368-6.
2
Lactate and pyruvate levels in the testicular vein of subfertile males with varicocele as a test for the theory of underlying hypoxia.对患有精索静脉曲张的亚生育男性睾丸静脉中的乳酸和丙酮酸水平进行检测,以验证潜在缺氧理论。
Andrologia. 1981 Jan-Feb;13(1):16-9. doi: 10.1111/j.1439-0272.1981.tb00002.x.
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Intraoperative internal spermatic vein phlebography in the subfertile male with varicocele.精索静脉曲张所致男性不育患者的术中精索内静脉静脉造影术。
Fertil Steril. 1978 Jun;29(6):669-75. doi: 10.1016/s0015-0282(16)43343-1.
4
Testis temperature, infertility, and the varicocele paradox.睾丸温度、不育症与精索静脉曲张悖论
Urology. 1980 Jul;16(1):7-10. doi: 10.1016/0090-4295(80)90321-0.
5
Internal spermatic vein prostaglandins in varicocele patients.精索静脉曲张患者的精索内静脉前列腺素
Fertil Steril. 1982 Feb;37(2):218-22. doi: 10.1016/s0015-0282(16)46043-7.
6
Inhibin B and anti-Müllerian hormone in spermatic vein of subfertile men with varicocele.抑制素 B 和抗苗勒管激素在精索静脉曲张的不育男性的精索静脉中的表达。
Reprod Sci. 2011 Jun;18(6):551-5. doi: 10.1177/1933719110393024. Epub 2011 Feb 1.
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Influence of surgically induced varicocele on testicular blood flow, temperature, and histology in adult rats and dogs.手术诱导的精索静脉曲张对成年大鼠和犬睾丸血流、温度及组织学的影响。
J Clin Invest. 1981 Jul;68(1):39-45. doi: 10.1172/jci110252.
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The varicocele and male infertility.精索静脉曲张与男性不育症。
Urol Clin North Am. 1981 Feb;8(1):41-51.
9
Right varicocele and hypoxia, crucial factors in male infertility: fluid mechanics analysis of the impaired testicular drainage system.右侧精索静脉曲张和缺氧,男性不育的关键因素:受损睾丸引流系统的流体力学分析
Reprod Biomed Online. 2006 Oct;13(4):510-5. doi: 10.1016/s1472-6483(10)60638-4.
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Glutathione-S-transferase-oxidative stress relationship in the internal spermatic vein blood of infertile men with varicocele.精索静脉曲张不育男性精索内静脉血中谷胱甘肽-S-转移酶与氧化应激的关系
Andrologia. 2015 Feb;47(1):47-51. doi: 10.1111/and.12234. Epub 2014 Jan 28.

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Insight into oxidative stress in varicocele-associated male infertility: part 1.精索静脉曲张相关男性不育症中氧化应激的研究进展:第 1 部分。
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