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果糖胺测定在糖尿病患者中的应用及其与代谢控制的关系。

The usefulness of fructosamine determination in diabetic patients and its relation to metabolic control.

作者信息

Daubresse J C, Laurent E, Ligny C, Bailly A, Lemy C, Duchateau A, Meunier J C

出版信息

Diabete Metab. 1987 Jun;13(3):217-21.

PMID:3609423
Abstract

In 116 diabetics and 101 control subjects, we measured both HbA1 and fructosamine values, neither could definitely separate the 2 populations. We observed an excellent correlation between both variables and between each of them and various other parameters of metabolic control. It appeared that the correlation with recent (4 weeks) diabetes control was better with fructosamine than with HbA1 levels. The opposite was true when a 8 week period was considered. The presence of diabetic complications did not modify the fructosamine levels. These results confirm the value of fructosamine measurement in the evaluation of recent diabetes control, but clearly, HbA1 determination remains the best parameter of long-term glycemic control.

摘要

在116名糖尿病患者和101名对照受试者中,我们测量了糖化血红蛋白(HbA1)和果糖胺值,两者均无法明确区分这两组人群。我们观察到这两个变量之间以及它们各自与代谢控制的各种其他参数之间存在极佳的相关性。似乎果糖胺与近期(4周)糖尿病控制的相关性比糖化血红蛋白水平更好。当考虑8周的时间段时,情况则相反。糖尿病并发症的存在并未改变果糖胺水平。这些结果证实了果糖胺测量在评估近期糖尿病控制中的价值,但显然,糖化血红蛋白测定仍然是长期血糖控制的最佳参数。

相似文献

1
The usefulness of fructosamine determination in diabetic patients and its relation to metabolic control.果糖胺测定在糖尿病患者中的应用及其与代谢控制的关系。
Diabete Metab. 1987 Jun;13(3):217-21.
2
Serum fructosamine (alkaline-reducing activity) for evaluation of glycemic control in diabetic patients.血清果糖胺(碱性还原活性)用于评估糖尿病患者的血糖控制情况。
Exp Clin Endocrinol. 1988 Dec;92(2):171-6. doi: 10.1055/s-0029-1210797.
3
[Assay for serum fructosamine in diabetes].[糖尿病患者血清果糖胺检测]
Quad Sclavo Diagn. 1986 Sep;22(3):303-11.
4
[Non-enzymatic glycosylation of plasma proteins in the evaluation of blood glucose balance in diabetics: determination of fructosamine].[糖尿病患者血糖平衡评估中血浆蛋白的非酶糖基化:果糖胺的测定]
Boll Soc Ital Biol Sper. 1987 Oct 31;63(10):881-8.
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Evaluation of diabetic control by using hemoglobin A1 and fructosamine.使用糖化血红蛋白A1和果糖胺评估糖尿病控制情况。
J Med Assoc Thai. 1990 Mar;73(3):130-5.
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Serum fructosamine/haemoglobin A1 ratio predicts the future changes in haemoglobin A1 in type 2 (non-insulin dependent) diabetic patients.
Clin Chim Acta. 1991 May 31;199(1):51-8. doi: 10.1016/0009-8981(91)90008-z.
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Glycated haemoglobin and glycated protein and glucose concentrations in necropsy blood samples.尸检血样中的糖化血红蛋白、糖化蛋白及葡萄糖浓度
J Clin Pathol. 1988 Apr;41(4):415-8. doi: 10.1136/jcp.41.4.415.
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Serial measurement of serum fructosamine and glycosylated haemoglobin as indices of glycaemic control in diabetic pregnancy.连续测定血清果糖胺和糖化血红蛋白作为糖尿病妊娠患者血糖控制指标
Ann Acad Med Singap. 1991 Nov;20(6):732-5.
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Comparison of HbA1 and fructosamine in diagnosis of glucose-tolerance abnormalities.糖化血红蛋白A1与果糖胺在诊断糖耐量异常中的比较。
Diabetes Care. 1990 Aug;13(8):898-900. doi: 10.2337/diacare.13.8.898.
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[Albumin or protein standardized fructosamine-plus, 2 new indices for evaluating diabetic metabolic status].[白蛋白或蛋白质标准化果糖胺加,用于评估糖尿病代谢状态的两个新指标]
Wien Klin Wochenschr Suppl. 1990;180:85-93; discussion 95-7.

引用本文的文献

1
Maternal serum fructosamine and maternofetal glucose and insulin homeostasis in normal pregnancy.正常妊娠中母血清果糖胺及母胎葡萄糖与胰岛素稳态
Arch Gynecol Obstet. 1990;248(1):1-11. doi: 10.1007/BF02389583.