Department of Nutrition and Dietetic, Faculty of Health Science, Gazi University, Bişkek Main St. 6. St No: 2, Emek, 06490, Turkey.
Curr Nutr Rep. 2022 Dec;11(4):675-681. doi: 10.1007/s13668-022-00441-0. Epub 2022 Sep 13.
Depression and anxiety are mood disorders that affect health and therefore quality of life and increase the global burden of disease. One of the possible mechanisms in the pathophysiology of these mood disorders has been reported as oxidative stress and inflammation. In the light of this information, it is important to determine the relationship between antioxidant nutrients (such as vitamin D) and these diseases. There are points where the brain regions involved in the pathophysiology of depression and anxiety and vitamin D metabolism intersect.
Low vitamin D levels are associated with increased symptoms of depression and anxiety. For this reason, vitamin D screening should be performed in the prevention and treatment planning of these mood disorders. Vitamin D, which has antioxidant properties and activity in brain tissue, is important for mood disorders preventions or treatments but serum levels must be followed.
抑郁和焦虑是影响健康、进而影响生活质量并增加全球疾病负担的心境障碍。这些心境障碍的病理生理学中可能的机制之一被报道为氧化应激和炎症。有鉴于此,确定抗氧化营养素(如维生素 D)与这些疾病之间的关系非常重要。在抑郁症和焦虑症的病理生理学以及维生素 D 代谢相互作用的脑区之间存在一些交汇点。
维生素 D 水平低与抑郁和焦虑症状加重有关。因此,在这些心境障碍的预防和治疗计划中应进行维生素 D 筛查。维生素 D 具有抗氧化特性和脑组织活性,对心境障碍的预防或治疗很重要,但必须监测血清水平。