Chen Wenjuan, Peng Chen, Zheng Jianfeng, Lu Xiya, Ding Yangfeng, Su Lina
Department of Dermatology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, People's Republic of China.
Institute of Psoriasis, Tongji University School of Medicine, Shanghai, People's Republic of China.
Clin Cosmet Investig Dermatol. 2022 Sep 7;15:1805-1808. doi: 10.2147/CCID.S374556. eCollection 2022.
Psoriasis is an immune-mediated systemic disease with multiple organs involvement, such as cardiovascular, live, gut, endocrine, and so on. Bullous pemphigoid (BP) is a rare comorbidity associated with psoriasis, while BP occurring in erythrodermic psoriasis (EP) is very rare. In this case, we reported a woman with severe EP who developed BP, in whom beta hemolytic streptococcus infection was a possible triggering factor. The complicated condition of such patients needs to draw attention of the physician and study further for better treatment.
银屑病是一种免疫介导的全身性疾病,可累及多个器官,如心血管、肝脏、肠道、内分泌等。大疱性类天疱疮(BP)是一种与银屑病相关的罕见合并症,而发生在红皮病型银屑病(EP)中的BP则极为罕见。在本病例中,我们报告了一名患有严重EP并发展为BP的女性,其中β溶血性链球菌感染可能是触发因素。这类患者的复杂病情需要引起医生的关注,并进一步研究以寻求更好的治疗方法。