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合并症作为美国人群癌症种族和民族差异的预测因素。

Comorbidity as a predictor of racial and ethnic disparities in cancer in the United States population.

作者信息

Akonde Maxwell, Gupta Rajat Das, Dakurah Ottovon Bismark, Hartsell Reston

机构信息

Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

African Cancer Institute, Stellenbosch University, South Africa.

出版信息

Public Health Pract (Oxf). 2021 Aug 26;2:100175. doi: 10.1016/j.puhip.2021.100175. eCollection 2021 Nov.

Abstract

AIMS

This study aims to examine the racial and ethnic disparity in cancer prevalence and determine if comorbidities can explain this disparity.

STUDY DESIGN

This was a cross-sectional study.

METHODS

The study examined cancer prevalence among adults who self-identified as White, Black, and Other races in the US population according to data from the 2017 National Health Interview Survey.

RESULTS

Cancer was 58.5% [OR = 0.415; 95% CI: 0.346-0.498] and 57.5% [OR = 0.425; 95%CI: 0.346-0.522] more likely to be found in the White compared to the Black adults and White compared to Other race adults, respectively. After adjusting for the comorbidities, the odds of cancer in White adults increased marginally compared to Black adults [OR = 0.407; 95%CI: 0.338-0.490] and decreased marginally compared to Other race adults [OR = 0.462; 95%CI: 0.374-0.569] even though the odds remained significant. Ever smoking, age of 50 years or more, Former and current alcohol consumption, overweight and obesity, being female and physical inactivity were found to be significantly associated with higher odds of cancer.

CONCLUSIONS

This study did identify a racial and ethnic disparity in cancer prevalence between White and Black adults and White and Other adult races. However, this racial and ethnic disparity could not be explained by comorbidities.

摘要

目的

本研究旨在探讨癌症患病率方面的种族和族裔差异,并确定合并症是否能够解释这种差异。

研究设计

这是一项横断面研究。

方法

该研究根据2017年美国国家健康访谈调查的数据,调查了美国人口中自我认定为白人、黑人及其他种族的成年人的癌症患病率。

结果

与黑人成年人相比,白人成年人患癌的可能性高58.5%[比值比(OR)=0.415;95%置信区间(CI):0.346 - 0.498];与其他种族成年人相比,白人成年人患癌的可能性高57.5%[OR = 0.425;95%CI:0.346 - 0.522]。在对合并症进行调整后,与黑人成年人相比,白人成年人患癌的几率略有增加[OR = 0.407;95%CI:0.338 - 0.490],与其他种族成年人相比略有降低[OR = 0.462;95%CI:0.374 - 0.569],尽管几率仍具有显著性。曾经吸烟、年龄在50岁及以上、既往和当前饮酒、超重和肥胖、女性以及缺乏身体活动被发现与患癌几率较高显著相关。

结论

本研究确实发现了白人成年人与黑人成年人以及白人成年人与其他种族成年人在癌症患病率方面的种族和族裔差异。然而,这种种族和族裔差异无法用合并症来解释。

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本文引用的文献

1
Cancer statistics, 2020.癌症统计数据,2020 年。
CA Cancer J Clin. 2020 Jan;70(1):7-30. doi: 10.3322/caac.21590. Epub 2020 Jan 8.
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Cancer statistics for African Americans, 2019.2019 年非裔美国人癌症统计数据。
CA Cancer J Clin. 2019 May;69(3):211-233. doi: 10.3322/caac.21555. Epub 2019 Feb 14.
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Breast Cancer Disparities: Socioeconomic Factors versus Biology.乳腺癌的差异:社会经济因素与生物学因素。
Ann Surg Oncol. 2017 Oct;24(10):2869-2875. doi: 10.1245/s10434-017-5977-1. Epub 2017 Aug 1.
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Causes of death among cancer patients.癌症患者的死因
Ann Oncol. 2017 Feb 1;28(2):400-407. doi: 10.1093/annonc/mdw604.
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Ageing as an Important Risk Factor for Cancer.衰老作为癌症的一个重要风险因素。
Anticancer Res. 2016 Oct;36(10):5009-5017. doi: 10.21873/anticanres.11069.

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