Sims C D, Chamberlain G V, Boyd I E, Lewis P J
Br J Obstet Gynaecol. 1978 Oct;85(10):761-6. doi: 10.1111/j.1471-0528.1978.tb15598.x.
Intravenous salbutamol and ethanol were compared as treatments for preterm labour, 42 patients being assigned randomly to salbutamol and 46 to ethanol. There was no statistically significant difference in outcome between patients in the two groups, the mean delay in delivery achieved being 15 days with salbutamol and 20 days with ethanol. Neither treatment was very effective since only 10 patients given salbutamol and 14 given ethanol had their delivery postponed to 37 weeks or later. Salbutamol was more rapidly acting than ethanol but produced more cardiovascular side effects.
对静脉注射沙丁胺醇和乙醇治疗早产进行了比较,42例患者被随机分配接受沙丁胺醇治疗,46例接受乙醇治疗。两组患者的治疗结果无统计学显著差异,使用沙丁胺醇时分娩平均延迟15天,使用乙醇时为20天。两种治疗方法都不是非常有效,因为使用沙丁胺醇的患者中只有10例、使用乙醇的患者中只有14例将分娩推迟至37周或更晚。沙丁胺醇比乙醇起效更快,但产生的心血管副作用更多。