Latimer K S, Kaswan R L, Sundberg J P
J Am Vet Med Assoc. 1987 Jun 1;190(11):1430-2.
A squamous cell carcinoma in situ (corneal intraepithelial neoplasia) was diagnosed in the right eye of an 11-year-old female Golden Retriever. Papillomavirus antigen was not detected in the excised tissues, and the tumor was suspected to be a sequel to previous injury. The tumor was removed by lamellar keratectomy, and the surgical bed was subjected to double freeze-thaw cryotherapy. Tumor regrowth was not apparent approximately one year after treatment.
一只11岁雌性金毛猎犬的右眼被诊断出患有原位鳞状细胞癌（角膜上皮内瘤变）。在切除的组织中未检测到乳头瘤病毒抗原，怀疑该肿瘤是先前损伤的后遗症。通过板层角膜切除术切除肿瘤，并对手术床进行双重冻融冷冻疗法。治疗后约一年，肿瘤未见明显复发。
