间位裂变反应对取代扁桃酸的降解作用
Degradation of substituted mandelic acids by meta fission reactions.
作者信息
Sze I S, Dagley S
出版信息
J Bacteriol. 1987 Aug;169(8):3833-5. doi: 10.1128/jb.169.8.3833-3835.1987.
Abstract
A strain of Acinetobacter lwoffii degraded 4-hydroxymandelic and 4-hydroxy-3-methoxymandelic acids to their corresponding benzoates, which were then hydroxylated by specific monooxygenases to yield, respectively, protocatechuic and 3-O-methylgallic acids; these were substrates for meta fission dioxygenases. The product formed from 3-O-methylgallate underwent slow spontaneous cyclization at pH 7 to release methanol.
摘要
一株鲁氏不动杆菌将4-羟基扁桃酸和4-羟基-3-甲氧基扁桃酸降解为相应的苯甲酸盐，然后这些苯甲酸盐被特定的单加氧酶羟基化，分别生成原儿茶酸和3-O-甲基没食子酸；这些是间位裂解双加氧酶的底物。由3-O-甲基没食子酸盐形成的产物在pH 7时缓慢自发环化以释放甲醇。
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