Torres-Collado Laura, García-de la Hera Manuela, Lopes Carla, Compañ-Gabucio Laura María, Oncina-Cánovas Alejandro, Notario-Barandiaran Leyre, González-Palacios Sandra, Vioque Jesús
Instituto de Investigación Sanitaria y Biomédica de Alicante, ISABIAL-UMH, Alicante, Spain.
Unidad de Epidemiología de la Nutrición, Departamento de Salud Pública, Historia de la Ciencia y Ginecología, Universidad Miguel Hernández (UMH), Alicante, Spain.
Front Nutr. 2022 Aug 30;9:997975. doi: 10.3389/fnut.2022.997975. eCollection 2022.
We assessed the association between usual olive oil consumption (OOC) and all-cause, cardiovascular (CVD) and cancer mortality in an adult population in Spain.
OOC was evaluated at baseline in 1,567 participants aged 20 years and older from the Valencia Nutrition Study in Spain using validated food frequency questionnaires. During an 18-year follow-up period, 317 died, 115 due to CVD and 82 due to cancer. Cox regression models were used to estimate adjusted hazard ratios (HR) and 95% confidence intervals (95%CI).
After adjusting for demographic and lifestyle factors, the OOC was associated with a lower risk of all-cause, CVD and cancer mortality. Compared to the less than once per month consumption, the consumption of up to one tablespoon per day was associated with a 9% lower risk of all-cause mortality (HR: 0.91; 95%CI: 0.68-1.22) and the consumption of 2 or more tablespoons with a 31% lower risk of all-cause mortality (HR: 0.69; 95%CI: 0.50-0.93; p-trend = 0.011). The consumption of 2 or more tablespoons per day was also associated with lower risk of mortality for CVD (HR: 0.54; 95%CI: 0.32-0.91; p-trend = 0.018) and cancer (HR: 0.49, 95%CI: 0.26-0.94; p-trend = 0.019).
Higher olive oil consumption was associated with lower long-term risk of all-cause, CVD and cancer mortality in an adult Mediterranean population. The maximum benefit was observed for the consumption of two or more tablespoons per day.
我们评估了西班牙成年人群中日常橄榄油摄入量（OOC）与全因死亡率、心血管疾病（CVD）死亡率和癌症死亡率之间的关联。
使用经过验证的食物频率问卷，对西班牙巴伦西亚营养研究中1567名年龄在20岁及以上的参与者在基线时的OOC进行了评估。在18年的随访期内，317人死亡，其中115人死于心血管疾病，82人死于癌症。使用Cox回归模型估计调整后的风险比（HR）和95%置信区间（95%CI）。
在调整了人口统计学和生活方式因素后，OOC与全因、心血管疾病和癌症死亡率风险降低相关。与每月食用少于一次相比，每天食用最多一汤匙橄榄油可使全因死亡率风险降低9%（HR：0.91；95%CI：0.68-1.22），每天食用两汤匙或更多则可使全因死亡率风险降低31%（HR：0.69；95%CI：0.50-0.93；p趋势=0.011）。每天食用两汤匙或更多橄榄油还与心血管疾病（HR：0.54；95%CI：0.32-0.91；p趋势=0.018）和癌症（HR：0.49，95%CI：0.26-0.94；p趋势=0.019）的较低死亡率风险相关。
在成年地中海人群中，较高的橄榄油摄入量与全因、心血管疾病和癌症死亡率的长期风险较低相关。每天食用两汤匙或更多橄榄油时观察到最大益处。
