紫杉醇联合奈达铂治疗卵巢癌的综合护理疗效分析。

Efficacy Analysis of Comprehensive Nursing in the Care of Ovarian Carcinoma Treated with Paclitaxel Combined with Nedaplatin.

机构信息

Department of Gynecology and Oncology, Shaanxi Cancer Hospital, Xi'an, 710061 Shaanxi, China.

Department of General Surgery, Shaanxi Cancer Hospital, Xi'an, 710061 Shaanxi, China.

出版信息

Comput Math Methods Med. 2022 Sep 6;2022:9398823. doi: 10.1155/2022/9398823. eCollection 2022.

DOI:10.1155/2022/9398823

PMID:36110573

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9470341/

Abstract

OBJECTIVE

To determine the effectiveness of comprehensive nursing in the care of ovarian carcinoma (OC) patients treated with paclitaxel (PTX) plus nedaplatin (NDP).

METHODS

The research population comprised 180 advanced OC patients who received treatment in the Shaanxi Cancer Hospital between November 2018 and November 2021. The enrolled cases were assigned to two groups based on different nursing plans: an observation group (OG) with 100 cases treated with comprehensive nursing and a control group (CG) with 80 cases intervened by conventional nursing. Intergroup comparisons were performed to identify statistical significance in terms of the following parameters: serum NGF, TK1, and CA15-3 levels; VAS, SAS, and SDS scores; nursing compliance; incidence of adverse reactions; and nursing satisfaction.

RESULTS

Compared with CG, OG showed the following: (1) lower posttreatment NGF, TK1, and CA15-3 levels; (2) lower scores of SAS and SDS; (3) higher nursing compliance; and (4) lower incidence of adverse reactions and higher nursing satisfaction after nursing.

CONCLUSIONS

Comprehensive nursing far outperformed conventional nursing in the care of advanced OC patients treated with PTX plus NDP, which is worth popularizing.

摘要

目的

评估紫杉醇（PTX）联合奈达铂（NDP）治疗卵巢癌（OC）患者中综合护理的效果。

方法

选取 2018 年 11 月至 2021 年 11 月在陕西省肿瘤医院治疗的 180 例晚期 OC 患者为研究对象，根据护理方案的不同分为观察组（100 例，综合护理）和对照组（80 例，常规护理）。比较两组患者的血清 NGF、TK1、CA15-3 水平、VAS、SAS、SDS 评分、护理依从性、不良反应发生率及护理满意度。