Jena Debkant, Manas Abhigyan, Venkateswararao C H, Salama Mohamed Tharwat, Ismail Prabu Mahin Syed, Basha Shaik Riyaz
Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, SOA Deemed to be University, K8 Kalinga Nagar, Bhubaneswar, Odhisa, India.
Senior Resident, Department of Dentistry, UP University of Medical Sciences, Saifai, Utter Pradesh, India.
J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S959-S961. doi: 10.4103/jpbs.jpbs_117_22. Epub 2022 Jul 13.
Evaluation of efficacy of bioactive glass (BAG), tricalcium phosphate, and ozone remineralizing agents on artificial carious lesion.
Freshly extracted 48 human premolar teeth were included for this study. Remineralization of demineralized teeth was done with respective remineralizing agents (Group A - calcium sodium phosphosilicate [BAG], Group B - tricalcium phosphate [Clinpro Tooth Crème], Group C - ozone remineralizing agents, and control group: Group D - deionized water) three times a day for 12 days for 4 min. The degree of demineralization and remineralization was evaluated with Vickers hardness number.
There was a decrease in microhardness from baseline to demineralization in all the groups. The difference in microhardness values from demineralization to remineralization in all the three test groups was found to be statistically highly significant.
BAG and Tricalcium phosphate had higher remineralizing capacity, which can be used clinically to treat early carious lesions.
评估生物活性玻璃(BAG)、磷酸三钙和臭氧再矿化剂对人工龋损的疗效。
本研究纳入48颗新鲜拔除的人类前磨牙。用各自的再矿化剂(A组 - 磷酸硅钙钠[BAG],B组 - 磷酸三钙[Clinpro Tooth Crème],C组 - 臭氧再矿化剂,对照组:D组 - 去离子水)对脱矿牙齿进行再矿化,每天3次,共12天,每次4分钟。用维氏硬度值评估脱矿和再矿化程度。
所有组从基线到脱矿时显微硬度均降低。在所有三个试验组中,从脱矿到再矿化的显微硬度值差异具有高度统计学意义。
BAG和磷酸三钙具有较高的再矿化能力,可在临床上用于治疗早期龋损。