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丙泊酚对牙科治疗过程中焦虑儿童行为的疗效及结果:一项干预性试验。

Propofol's Efficacy and Outcomes on Anxious Children's Behavior in the Course of Dental Therapy: An Interventional Trial.

作者信息

Singh Swati, Neyaz Nudrat, Tanwar Aditi S, Patil Anand N, Khan Asim M, Kakti Ateet

机构信息

Department of Pediatric and Preventive Dentistry, Hazaribag College of Dental Sciences and Hospital, Hazaribagh, Jharkhand, India.

Consultant Pedodontist, Rama Dental Clinic, Patna, Bihar, India.

出版信息

J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S550-S553. doi: 10.4103/jpbs.jpbs_155_22. Epub 2022 Jul 13.

DOI:10.4103/jpbs.jpbs_155_22
PMID:36110702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9469281/
Abstract

INTRODUCTION

Tranquility therapies have recently been more popular as a means of reducing anxiety amongst children in the course of painful diagnostic and therapeutic procedures. As a result, a variety of techniques (oral tranquility, intravenous (IV) tranquility) have been developed to assist practitioners in order to deal with such instances. The goal of this trial was to see how effective propofol could be in calming anxious youngsters during the course of dental therapy. The interventional investigation was undertaken at the Hazaribag College of Dental Sciences and Hospital in Jharkhand.

MATERIALS AND METHODS

To assess the outcomes of intravenous propofol on their performance in the course of therapy, 40 children within the age group of 3-6 years pursuing good physical health but uncooperative in nature (negative or definitely negative, bestowing to Frankel's performance scale) were comprised in the study. The performance rating scale was utilized to assess their performance throughout the therapy (BRS). In addition, the point of tranquility was assessed beforehand. Mann-Whitney test was utilized to equate male and female points of performance along with gradations of drowsiness. The value for significance was fixed at 0.05.

RESULTS

All participants' performance and point of tranquility in the course of therapy were promising, and therapy was accomplished for everyone. Mann-Whitney test revealed no statistically significant differences in point of performance, or gradation of drowsiness amid males and females. Pearson's correlation coefficient revealed a strong positive association of therapy time with awakening time.

CONCLUSION

Intravenous propofol deep tranquility in the presence of an anesthesiologist was found to be beneficial in restraining nervous and recalcitrant youngsters in the course of dental therapy.

摘要

引言

近年来,宁静疗法作为一种在痛苦的诊断和治疗过程中减轻儿童焦虑的方法越来越受欢迎。因此,已经开发出了多种技术(口服镇静、静脉注射镇静)来帮助从业者应对此类情况。本试验的目的是观察丙泊酚在牙科治疗过程中使焦虑的儿童镇静的效果如何。这项干预性研究在贾坎德邦哈扎里巴格牙科学院和医院进行。

材料与方法

为了评估静脉注射丙泊酚对治疗过程中儿童表现的影响,本研究纳入了40名年龄在3至6岁之间、身体健康但生性不合作(根据弗兰克尔表现量表为阴性或绝对阴性)的儿童。使用表现评定量表评估他们在整个治疗过程中的表现(BRS)。此外,预先评估镇静程度。使用曼-惠特尼检验比较男性和女性的表现得分以及嗜睡程度。显著性值设定为0.05。

结果

所有参与者在治疗过程中的表现和镇静程度都很理想,并且每个人的治疗都完成了。曼-惠特尼检验显示,男性和女性在表现得分或嗜睡程度上没有统计学上的显著差异。皮尔逊相关系数显示治疗时间与苏醒时间呈强正相关。

结论

发现在麻醉医生在场的情况下静脉注射丙泊酚进行深度镇静,有助于在牙科治疗过程中抑制紧张和倔强的儿童。

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Acceptability of intravenous propofol sedation for adolescent dental care.青少年牙科治疗中静脉注射丙泊酚镇静的可接受性。
Eur Arch Paediatr Dent. 2020 Jun;21(3):295-302. doi: 10.1007/s40368-019-00482-0. Epub 2019 Oct 8.
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Guidelines for Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures.诊断和治疗操作中儿科患者镇静前、镇静期间及镇静后监测与管理指南。
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Comparison of the Sedation Quality of Etomidate, Propofol, and Midazolam in Combination with Fentanyl During Phacoemulsification Cataract Surgery: A Double-Blind, Randomized, Controlled, Clinical Trial.依托咪酯、丙泊酚和咪达唑仑联合芬太尼在白内障超声乳化手术中的镇静质量比较:一项双盲、随机、对照临床试验
Anesth Pain Med. 2019 Apr 27;9(2):e87415. doi: 10.5812/aapm.87415. eCollection 2019 Apr.
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Distraction as a technique to control pain in pediatric patients during venipuncture. A narrative review of literature.分散注意力作为儿科患者静脉穿刺时控制疼痛的一种技术。文献综述。
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Stress Reduction through Audio Distraction in Anxious Pediatric Dental Patients: An Adjunctive Clinical Study.通过音频分散注意力减轻焦虑儿科牙科患者的压力:一项辅助性临床研究。
Int J Clin Pediatr Dent. 2014 Sep-Dec;7(3):149-52. doi: 10.5005/jp-journals-10005-1254. Epub 2015 Feb 9.
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