Ziaei Hezarjaribi Hajar, Saberi Reza, Fakhar Mahdi, Sadeghian Najmeh
Iranian National Registry Center for Lophomoniasis (INRCL) and Toxoplasmosis (INRCT), School of Medicine, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Interdiscip Perspect Infect Dis. 2022 Sep 6;2022:8359859. doi: 10.1155/2022/8359859. eCollection 2022.
Male urethritis is one of the most common genital tract syndromes. Though the number of patients with urethritis is increasing worldwide, the cause of many cases of non-gonococcal urethritis (NGU) is still unknown.
This study aimed to delineate the association between () infection and male urethritis.
The literature was searched in PubMed, Scopus, and Web of Science databases using the search terms "urethritis," "," "trichomoniasis," and "male urethritis" up to February 2020. Overall risk difference(RD) was applied to assess the relationship between infection and male urethritis.
In total, seven articles were included in this systematic review and meta-analysis study. Our meta-analysis involved the review of case-control studies, including 2,242 urethritis cases and 929 individuals as controls. Among subjects examined for trichomoniasis, in the case group, 211 males were infected, and in the control group, 32 individuals were infected. The overall risk difference (RD) was 0.06, and the total reported value was 0.00001. Although the result of our meta-analysis was not significant, it was shown that the risk of urethritis is 0.06 more in trichomoniasis patients than in the non-exposed group.
Findings from the included papers showed that trichomoniasis is not a risk factor for male urethritis. Although trichomoniasis alone is not the main cause of urethritis, it can be considered one of the risk factors in male urethritis. Therefore, in the future, it is necessary to perform further studies to clarify the detailed association between infection and urethritis risk in male patients.
男性尿道炎是最常见的生殖道综合征之一。尽管全球尿道炎患者数量在增加，但许多非淋菌性尿道炎（NGU）病例的病因仍不清楚。
本研究旨在阐明（）感染与男性尿道炎之间的关联。
截至2020年2月，在PubMed、Scopus和Web of Science数据库中使用搜索词“尿道炎”、“（此处原文缺失具体病原体名称）”、“滴虫病”和“男性尿道炎”进行文献检索。应用总体风险差异（RD）来评估（此处原文缺失具体病原体名称）感染与男性尿道炎之间的关系。
本系统评价和荟萃分析研究共纳入7篇文章。我们的荟萃分析涉及对病例对照研究的回顾，包括2242例尿道炎病例和929例个体作为对照。在接受滴虫病检查的受试者中，病例组有211名男性感染，对照组有32名个体感染。总体风险差异（RD）为0.06，报告的总P值为0.00001。尽管我们的荟萃分析结果不显著，但结果表明滴虫病患者患尿道炎的风险比未暴露组高0.06。
纳入论文的研究结果表明，滴虫病不是男性尿道炎的危险因素。虽然单独的滴虫病不是尿道炎的主要原因，但它可被视为男性尿道炎的危险因素之一。因此，未来有必要进行进一步研究，以阐明（此处原文缺失具体病原体名称）感染与男性患者尿道炎风险之间的详细关联。
