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High-performance liquid chromatography and preliminary pharmacokinetics of nicomorphine and its metabolites 3-nicotinoyl- and 6-nicotinoylmorphine and morphine.

作者信息

Koopman-Kimenai P M, Vree T B, Cress-Tijhuis M W, Booy L H, Drijkoningen G

出版信息

J Chromatogr. 1987 May 15;416(2):382-7. doi: 10.1016/0378-4347(87)80524-8.

DOI:10.1016/0378-4347(87)80524-8
PMID:3611270
Abstract
摘要

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Rectal administration of nicomorphine in patients improves biological availability of morphine and its glucuronide conjugates.
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2
Morphine and morphine-glucuronide concentrations in plasma and CSF during long-term administration of oral morphine.口服吗啡长期给药期间血浆和脑脊液中吗啡及吗啡 - 葡萄糖醛酸苷的浓度
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3
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