Department of Nursing, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, Sichuan, China.
Bioinformatics Lab, Hangzhou Taoxue Space Ltd, Hangzhou, Zhejiang, China.
Sleep Med. 2022 Dec;100:198-205. doi: 10.1016/j.sleep.2022.08.025. Epub 2022 Sep 6.
Menopausal symptoms exist in most climacteric women, which can harm the quality and satisfaction of life for them. Moreover, a series of ineluctable negative life changes experienced in middle-age usually make the situation more complicated and stressful. We aimed to determine the trajectories and influential factors of sleep quality and menopausal symptoms and their longitudinal interrelationships among climacteric women.
A total of 1875 community-dwelling climacteric women were included in this study. The Pittsburgh Sleep Quality Index (PSQI) and the Menopause Rating Scale (MRS) were adopted to assess sleep quality and menopausal symptoms, respectively. Data were collected 4 times from March 2019 to December 2019, at a 3-month interval.
The Cross-lagged analysis showed that worse sleep quality and more severe menopausal symptoms over time after controlling for specified covariates, and more severe menopausal symptoms were predicted by declined sleep quality. The Generalized estimation equation model showed that education level, marital status, chronic diseases, life events, income, and age were the influential factors of sleep quality, while menopausal symptoms were impacted by marital status and income.
Increasing negative sleep quality and more severe menopausal symptoms over time contribute to the health burden of climacteric women. Menopausal symptoms could be alleviated by sleep quality improvement, which is influenced by education level, marital status, chronic diseases, life events, age, and economic factors.
绝经期症状存在于大多数更年期女性中，这会损害她们的生活质量和满意度。此外，中年时期经历的一系列不可避免的负面生活变化通常会使情况更加复杂和有压力。我们旨在确定更年期女性睡眠质量和更年期症状的轨迹和影响因素，以及它们之间的纵向相互关系。
本研究共纳入 1875 名社区居住的更年期女性。采用匹兹堡睡眠质量指数（PSQI）和更年期评定量表（MRS）分别评估睡眠质量和更年期症状。数据于 2019 年 3 月至 2019 年 12 月间每隔 3 个月收集 4 次。
交叉滞后分析表明，在控制了特定协变量后，随着时间的推移，睡眠质量恶化和更年期症状加重，而更年期症状更严重的预示着睡眠质量下降。广义估计方程模型表明，教育水平、婚姻状况、慢性疾病、生活事件、收入和年龄是睡眠质量的影响因素，而更年期症状受婚姻状况和收入的影响。
随着时间的推移，负面睡眠质量的增加和更年期症状的加重会增加更年期女性的健康负担。改善睡眠质量可以缓解更年期症状，而睡眠质量受教育水平、婚姻状况、慢性疾病、生活事件、年龄和经济因素的影响。
