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非酒精性脂肪性肝病合并睡眠呼吸暂停综合征患者的管理。

Management of non-alcoholic fatty liver disease patients with sleep apnea syndrome.

机构信息

Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.

出版信息

World J Gastroenterol. 2022 Nov 21;28(43):6099-6108. doi: 10.3748/wjg.v28.i43.6099.

DOI:10.3748/wjg.v28.i43.6099
PMID:36483151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9724487/
Abstract

Nonalcoholic fatty liver disease (NAFLD) is strongly associated with sleep apnea syndrome (SAS). Many NAFLD patients have SAS, and obstructive sleep apnea hypopnea syndrome is also considered to be an independent risk factor for NAFLD, as it contributes to the progression of NAFLD oxidative stress, lipid peroxidation, inflammation, and insulin resistance. This review aims to provide some recommendations for the management of NAFLD patients with SAS, including diet, exercise, weight loss, and continuous positive airway pressure. This review also highlights the importance of effective strategies in NAFLD prevention and treatment.

摘要

非酒精性脂肪性肝病（NAFLD）与睡眠呼吸暂停综合征（SAS）密切相关。许多 NAFLD 患者存在 SAS，而阻塞性睡眠呼吸暂停低通气综合征也被认为是 NAFLD 的独立危险因素，因为它可导致 NAFLD 的氧化应激、脂质过氧化、炎症和胰岛素抵抗进展。本综述旨在为 SAS 合并 NAFLD 患者的管理提供一些建议，包括饮食、运动、减肥和持续气道正压通气。本综述还强调了在 NAFLD 预防和治疗中采取有效策略的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89f1/9724487/61eff2ebb10b/WJG-28-6099-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89f1/9724487/61eff2ebb10b/WJG-28-6099-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89f1/9724487/61eff2ebb10b/WJG-28-6099-g001.jpg

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