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成人复发性巨大鼻咽血管纤维瘤累及鼻窦、眼眶及颅内的多学科管理

Multidiscipline management of giant reccurent nasopharyngeal angiofibroma which extends to paranasal sinuses, orbita, and intracranial in adult.

作者信息

Rahmadiyanto Yoga, Romdhoni Achmad Chusnu

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

出版信息

Int J Surg Case Rep. 2022 Oct;99:107579. doi: 10.1016/j.ijscr.2022.107579. Epub 2022 Sep 7.

Abstract

Nasopharyngeal angiofibroma (NA) is a benign, slowly growing tumour that affects males in their early puberty, and rarely men over 25 years of age. There was an interesting case of a giant recurrent NA in a 62-year-old male, which is challenging to manage due to wide tumour expansion to paranasal sinuses, orbital and intracranial. In cases of large angiofibromas disease, preoperative embolization should be performed to prevent profuse bleeding. Wide expansion of NA can cause post extirpation large defects of the tumour so that optimal defect closure techniques are needed to restore the aesthetics and function of the disturbed organs. This case's diagnosis and management of this disease was carried out by multidisciplinary discussion, and surgical extirpation of the joint tumour was performed in Dr. Soetomo General Academic Teaching Hospital. The tumour was removed by medial maxillectomy with an extended Killian right lateral rhinotomy approach followed by tumour defects reconstruction. The follow up showed that there were still tumour residue and suspicious intracranial abscess, but the patient had no complaint during follow-up for ten months after surgery.

摘要

鼻咽血管纤维瘤(NA)是一种良性、生长缓慢的肿瘤,好发于青春期早期男性,25岁以上男性罕见。有一例有趣的病例,一名62岁男性患有巨大复发性NA,由于肿瘤广泛扩展至鼻窦、眼眶和颅内,治疗颇具挑战性。对于大型血管纤维瘤病病例,应进行术前栓塞以防止大出血。NA的广泛扩展可导致肿瘤切除后出现大的缺损,因此需要采用最佳的缺损闭合技术来恢复受影响器官的美观和功能。该病例的疾病诊断和治疗通过多学科讨论进行,并在苏托莫综合学术教学医院进行了联合肿瘤的手术切除。采用内侧上颌骨切除术加改良Killian右侧鼻侧切开术切除肿瘤,随后进行肿瘤缺损重建。随访显示仍有肿瘤残留和可疑颅内脓肿,但患者术后十个月的随访期间无不适主诉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0008/9568708/2b0c62433417/gr1.jpg

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