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鼻咽血管纤维瘤:老年患者中被遗忘的疾病

Nasopharyngeal Angiofibroma: A Forgotten Entity in Older Patients.

作者信息

Stubbs Vanessa C, Miller Lauren E, Parasher Arjun K, Glicksman Jordan T, Adappa Nithin D, Palmer James

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

出版信息

Clin Med Insights Case Rep. 2019 Apr 23;12:1179547619841062. doi: 10.1177/1179547619841062. eCollection 2019.

DOI:10.1177/1179547619841062
PMID:31040732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6480991/
Abstract

INTRODUCTION

Nasopharyngeal angiofibroma (NA) characteristically affects adolescent men. Although benign, these tumors can cause local destruction and surgical resection is warranted.

OBJECTIVE

We present a case of a 62-year-old man with nasal congestion and epistaxis, found to be a right NA on pathology. We also present a review of the available NA staging systems.

FINDINGS

In this case of NA, imaging revealed an aggressive, hypervascular mass in the nasal cavity with involvement of the middle cranial fossa and cavernous sinus. The patient underwent complete endoscopic surgical resection following vascular embolization.

CONCLUSIONS

Although it is rare, NA should not be disregarded in the elderly population.

摘要

引言

鼻咽血管纤维瘤(NA)典型地好发于青春期男性。尽管这些肿瘤是良性的,但可导致局部破坏,因此有必要进行手术切除。

目的

我们报告一例62岁男性患者,有鼻塞和鼻出血症状,病理检查发现为右侧鼻咽血管纤维瘤。我们还对现有的鼻咽血管纤维瘤分期系统进行了综述。

结果

在该鼻咽血管纤维瘤病例中,影像学检查显示鼻腔内有一个侵袭性、高血运肿块,累及中颅窝和海绵窦。患者在血管栓塞后接受了完整的内镜手术切除。

结论

尽管罕见,但在老年人群中不应忽视鼻咽血管纤维瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b630/6480991/803af028a5dc/10.1177_1179547619841062-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b630/6480991/6de9d9808451/10.1177_1179547619841062-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b630/6480991/53eb2ef73186/10.1177_1179547619841062-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b630/6480991/803af028a5dc/10.1177_1179547619841062-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b630/6480991/6de9d9808451/10.1177_1179547619841062-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b630/6480991/53eb2ef73186/10.1177_1179547619841062-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b630/6480991/803af028a5dc/10.1177_1179547619841062-fig3.jpg

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本文引用的文献

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Mol Clin Oncol. 2018 Dec;9(6):702-704. doi: 10.3892/mco.2018.1735. Epub 2018 Oct 5.
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Nasopharyngeal Angiofibroma: A Clinical, Histopathological and Immunohistochemical Study of 42 Cases with Emphasis on Stromal Features.鼻咽血管纤维瘤:42例临床、组织病理学及免疫组织化学研究,重点关注间质特征
Head Neck Pathol. 2018 Mar;12(1):52-61. doi: 10.1007/s12105-017-0824-z. Epub 2017 May 15.
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Management of nasopharyngeal angiofibroma in a 72-year-old male through a sublabial and buccolabial incision approach: A case report and literature review.
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Multidiscipline management of giant reccurent nasopharyngeal angiofibroma which extends to paranasal sinuses, orbita, and intracranial in adult.成人复发性巨大鼻咽血管纤维瘤累及鼻窦、眼眶及颅内的多学科管理
Int J Surg Case Rep. 2022 Oct;99:107579. doi: 10.1016/j.ijscr.2022.107579. Epub 2022 Sep 7.
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Current approach of juvenile nasopharyngeal angiofibroma: a case series.青少年鼻咽血管纤维瘤的当前治疗方法:病例系列。
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经唇下和颊唇切口入路治疗72岁男性鼻咽血管纤维瘤:病例报告及文献复习
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