School of Public Health, College of Health Science, Woldia University, Woldia, Ethiopia.
Department of Public Health, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia.
Sci Rep. 2022 Sep 19;12(1):15664. doi: 10.1038/s41598-022-19909-8.
Diabetes mellitus is a global public health problem. Glycemic control is a major public health problem. Diabetes results from elevated levels of glycaemia such as increased glucose and glycated hemoglobin, and controlling glycaemia is an integral component of the management of diabetes. Glycemic control in children is particularly difficult to achieve. Identifying determinants of poor glycemic control is important for early modification of diabetic related end organ damages. This study was aimed to assess the status of glycemic control and associated factors among pediatric diabetes mellitus patients in northwest Ethiopia. Facility-based cross sectional retrospective cohort study design was used and this study was conducted from September, 2015 to February, 2018. Simple random sampling was used to select 389 samples. Data were collected using an extraction checklist. Data were entered into Epi-data - 4.6, and analyzed using Stata-16. Finally, multivariable binary logistic regression was done. Poor glycemic control was more common among pediatric patients 39.3% (95% CI 34.6, 44.3). Treatment discontinuation (AOR 2.42, 95% CI 1.25, 4.69), age (AOR 1.15, 95% CI 1.03, 1.28) and treatment dose (AOR 0.96, 95 CI 0.92, 0.99) were significantly associated with poor glycemic control. Prevalence of poor glycemic control was high. Patient's age, history of treatment discontinuation and dose of treatment were the significant contributing factors to poor glycemic control. These need to be addressed to attain the objective of adequate glycemic control.
糖尿病是一个全球性的公共卫生问题。血糖控制是一个主要的公共卫生问题。糖尿病是由于血糖升高引起的,如葡萄糖和糖化血红蛋白升高,控制血糖是糖尿病管理的一个组成部分。儿童的血糖控制尤其难以实现。确定血糖控制不佳的决定因素对于早期改变糖尿病相关的终末器官损害非常重要。本研究旨在评估埃塞俄比亚西北部儿科糖尿病患者的血糖控制状况及相关因素。采用基于机构的横断面回顾性队列研究设计,于 2015 年 9 月至 2018 年 2 月进行。采用简单随机抽样选择了 389 名样本。使用提取检查表收集数据。数据输入到 Epi-data-4.6 中,并使用 Stata-16 进行分析。最后进行了多变量二元逻辑回归。39.3%(95%CI 34.6,44.3)的儿科患者血糖控制不佳更为常见。治疗中断(AOR 2.42,95%CI 1.25,4.69)、年龄(AOR 1.15,95%CI 1.03,1.28)和治疗剂量(AOR 0.96,95 CI 0.92,0.99)与血糖控制不佳显著相关。血糖控制不佳的患病率较高。患者的年龄、治疗中断的病史和治疗剂量是导致血糖控制不佳的重要因素。需要解决这些问题,以达到适当血糖控制的目标。