Zhou Enhui, Xue Xiaocheng, Liu Xing, Zhang Yi
Department of Otorhinolaryngology, Pudong New Area Gongli Hospital, Shanghai, China.
Ear Nose Throat J. 2025 Mar;104(1_suppl):174S-176S. doi: 10.1177/01455613221127586. Epub 2022 Sep 19.
Malignant proliferating trichilemmal tumor (MPTT) is a dermal adnexal tumor originated from the external root sheath of hair follicles. In this article, we reported a rare case of auricular MPTT in a 65-year-old male with gradually enlarging and bleeding mass on the right auricle measuring 30 × 20 × 12 mm in size and detailed the surgical strategy for therapy. The diagnosis of MPTT was established primarily by histopathological observation with abrupt keratinization, cytological atypia, abnormal mitoses, and infiltrating margins. Following extensive excision, no recurrence was noted for 14 months. We also discuss its clinicopathological features, differential diagnoses, and treatment methods and review the relevant literature in this regard.
恶性增生性外毛根鞘瘤（MPTT）是一种起源于毛囊外根鞘的皮肤附属器肿瘤。在本文中，我们报告了一例罕见的耳部MPTT病例，患者为一名65岁男性，右耳廓有一个逐渐增大且出血的肿物，大小为30×20×12毫米，并详细阐述了治疗的手术策略。MPTT的诊断主要通过组织病理学观察确定，表现为突然角化、细胞异型性、异常核分裂以及浸润性边缘。广泛切除后，14个月内未发现复发。我们还讨论了其临床病理特征、鉴别诊断和治疗方法，并回顾了这方面的相关文献。
