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虫媒病毒感染的神经系统表现

Nervous System Manifestations of Arboviral Infections.

作者信息

Chauhan Lakshmi, Matthews Elizabeth, Piquet Amanda L, Henao-Martinez Andrés, Franco-Paredes Carlos, Tyler Kenneth L, Beckham David, Pastula Daniel M

机构信息

Division of Infectious Diseases, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045 USA.

Neuro-Infectious Diseases Group, Department of Neurology and Division of Infectious Diseases, University of Colorado, Anschutz Medical Center, Aurora, CO USA.

出版信息

Curr Trop Med Rep. 2022;9(4):107-118. doi: 10.1007/s40475-022-00262-9. Epub 2022 Sep 15.

DOI:10.1007/s40475-022-00262-9
PMID:36124288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9476420/
Abstract

PURPOSE OF REVIEW

Complex environmental factors and human intervention influence the spread of arthropod vectors and the cycle of transmission of arboviruses. The spectrum of clinical manifestations is diverse, ranging from serious presentations like viral hemorrhagic fever (e.g., dengue, yellow fever, rift valley fever) or shock syndromes (e.g., dengue virus) to organ-specific illness like meningoencephalitis.

RECENT FINDINGS

A spectrum of clinical neurologic syndromes with potential acute devastating consequences or long-term sequelae may result from some arboviral infections.

SUMMARY

In this review, we describe some of the most frequent and emerging neuro-invasive arboviral infections, spectrum of neurologic disorders including encephalitis, meningitis, myelitis or poliomyelitis, acute demyelinating encephalomyelitis, Guillain-Barré syndrome, and ocular syndromes.

摘要

综述目的

复杂的环境因素和人为干预会影响节肢动物媒介的传播以及虫媒病毒的传播周期。临床表现范围多样,从严重症状如病毒性出血热(如登革热、黄热病、裂谷热)或休克综合征(如登革热病毒)到器官特异性疾病如脑膜脑炎。

最新发现

某些虫媒病毒感染可能导致一系列具有潜在急性严重后果或长期后遗症的临床神经综合征。

总结

在本综述中,我们描述了一些最常见和新出现的神经侵袭性虫媒病毒感染、神经疾病谱,包括脑炎、脑膜炎、脊髓炎或脊髓灰质炎、急性脱髓鞘性脑脊髓炎、格林-巴利综合征和眼部综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed3a/9476420/0db6aad39582/40475_2022_262_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed3a/9476420/0db6aad39582/40475_2022_262_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed3a/9476420/0db6aad39582/40475_2022_262_Fig1_HTML.jpg

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