School of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Math Biosci Eng. 2022 Aug 3;19(11):11137-11153. doi: 10.3934/mbe.2022519.
The traditional manual breast cancer diagnosis method of pathological images is time-consuming and labor-intensive, and it is easy to be misdiagnosed. Computer-aided diagnosis of WSIs gradually comes into people*s sight. However, the complexity of high-resolution breast cancer pathological images poses a great challenge to automatic diagnosis, and the existing algorithms are often difficult to balance the accuracy and efficiency. In order to solve these problems, this paper proposes an automatic image segmentation method based on dual-path feature extraction network for breast pathological WSIs, which has a good segmentation accuracy. Specifically, inspired by the concept of receptive fields in the human visual system, dilated convolutional networks are introduced to encode rich contextual information. Based on the channel attention mechanism, a feature attention module and a feature fusion module are proposed to effectively filter and combine the features. In addition, this method uses a light-weight backbone network and performs pre-processing on the data, which greatly reduces the computational complexity of the algorithm. Compared with the classic models, it has improved accuracy and efficiency and is highly competitive.
传统的病理图像乳腺癌手动诊断方法既耗时又费力,容易误诊。基于全切片图像(WSI)的计算机辅助诊断逐渐受到人们的关注。然而,高分辨率乳腺癌病理图像的复杂性给自动诊断带来了巨大的挑战,现有的算法往往难以平衡准确性和效率。为了解决这些问题,本文提出了一种基于双路径特征提取网络的自动图像分割方法,用于乳腺病理 WSI,具有良好的分割准确性。具体来说,受人类视觉系统感受野概念的启发,引入了扩张卷积网络来编码丰富的上下文信息。基于通道注意力机制,提出了特征注意力模块和特征融合模块,以有效筛选和组合特征。此外,该方法使用轻量级骨干网络并对数据进行预处理,大大降低了算法的计算复杂度。与经典模型相比,它提高了准确性和效率,具有很强的竞争力。