School of Medicine, University College Dublin, Department of Respiratory and Sleep Medicine, St. Vincent's University Hospital, Dublin, Ireland.
Curr Opin Pulm Med. 2022 Nov 1;28(6):543-551. doi: 10.1097/MCP.0000000000000922. Epub 2022 Sep 21.
The chronic obstructive pulmonary disease and obstructive sleep apnoea overlap syndrome is associated with higher morbidity and mortality rates than either disease alone. There is evidence of a bidirectional relationship between the two conditions, with the overlap syndrome encompassing a spectrum of clinical phenotypes.
This review examines the evidence for the various factors that determine the overlap syndrome, the impact overlap syndrome has on co-morbidities, and implications for diagnosis and treatment.
The accurate diagnosis of the overlap syndrome is critical given its implications for treatment optimisation and reduction in healthcare utilisation and costs.
慢性阻塞性肺疾病和阻塞性睡眠呼吸暂停重叠综合征的发病率和死亡率均高于任一单独疾病。这两种疾病之间存在双向关系的证据，重叠综合征包含一系列临床表型。
本综述检查了决定重叠综合征的各种因素的证据，重叠综合征对合并症的影响，以及对诊断和治疗的影响。
鉴于重叠综合征对治疗优化以及减少医疗保健利用和成本的影响，准确诊断重叠综合征至关重要。
