铁（III）催化的电化学方法选择性裂解苯甲酰胺的C-N键
Fe(iii)-catalysed selective C-N bond cleavage of -phenylamides by an electrochemical method.
作者信息
Xu Yiwen, Long Yang, Ye Runyou, Li Qiang, Ke Fang, Zhou Xiangge
机构信息
College of Chemistry, Sichuan University Wangjiang Road 29 Chengdu 610064 China
School of Pharmacy, Fujian Provincial Key Laboratory of Natural Medicine Pharmacology, Fujian Medical University Fuzhou 350004 China
出版信息
RSC Adv. 2022 Aug 25;12(37):24217-24221. doi: 10.1039/d2ra04709h. eCollection 2022 Aug 22.
Abstract
An Fe(iii)-catalysed transformation of secondary -phenyl substituted amides to primary amides by an electrochemical method is developed. Regioselective aryl C-H oxygenation occurs during the reaction, promoting selective C(phenyl)-N bond cleavage to form primary amides in yields of up to 92%.
摘要
开发了一种通过电化学方法将仲苯基取代酰胺转化为伯酰胺的铁（III）催化反应。反应过程中发生区域选择性芳基C-H氧化，促进选择性C（苯基）-N键断裂，以高达92%的产率形成伯酰胺。
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