Victor Babes National Institute of Pathology, Bucharest, Romania - "Prof. Dr. Alexandru Obregia" Clinical Hospital of Psychiatry, Bucharest, Romania - Faculty of Medicine, Titu Maiorescu University, Bucharest, Romania.
"Prof. Dr. Alexandru Obregia" Clinical Hospital of Psychiatry, Bucharest, Romania.
Ann Ist Super Sanita. 2022 Jul-Sep;58(3):183-191. doi: 10.4415/ANN_22_03_07.
To identify developmental symptoms reported at firsts doctor visits by parents of children later diagnosed with Autism Spectrum Disorder (ASD).
Cohort study.
The study was conducted in the Department of Psychiatry Research of "Prof. Dr. Alexandru Obregia" Clinical Psychiatry Hospital from Bucharest between September 2019 and May 2021.
105 cases: 82 boys and 23 girls, 100 children with autism, and 5 patients with Asperger's syndrome.
ASD was diagnosed according to the DSM-5 criteria, ADOS-1 (Autism Diagnostic Observation Schedule, 1st Edition) and/or ADI-R (Autism Diagnostic Interview-Revised) tests scores; features reported by the parents for which they presented to the doctor for a diagnosis were taken into consideration.
The age at first presentation to the doctor; the most common early signs reported by the parents of children with ASD.
The age at first presentation to the doctor in our group was between 9 months and 14 years. The most common early signs reported by parents were: delayed language development, deficits in understanding verbal instructions/indications, and hyperactivity and aggressivity. In the case of patients with Asperger's syndrome, the reported features were hyperactivity and aggressivity, learning difficulties, and social interaction problems. Regression and delay in language development occurred more often in boys than in girls.
Parents, as well as family doctors or paediatricians, should pay great attention to the children's behaviour, alongside their cognitive and language development. Early detection is essential for early intervention and our results can be used to develop training programs for parents and paediatricians for early recognition of ASD.
识别首次就诊时父母报告的发育症状，这些儿童后来被诊断为自闭症谱系障碍（ASD）。
队列研究。
该研究于 2019 年 9 月至 2021 年 5 月在布加勒斯特“Alexandru Obregia”临床精神病学医院精神病学研究系进行。
105 例：82 名男孩和 23 名女孩，100 名自闭症儿童和 5 名阿斯伯格综合征患者。
根据 DSM-5 标准、ADOS-1（自闭症诊断观察量表，第 1 版）和/或 ADI-R（自闭症诊断访谈修订版）测试评分诊断 ASD；考虑到父母为诊断而向医生报告的特征。
首次就诊医生的年龄；父母报告的 ASD 儿童最常见的早期症状。
我们组首次就诊医生的年龄在 9 个月至 14 岁之间。父母报告的最常见早期症状包括：语言发育迟缓、理解口头指令/指示的能力不足、多动和攻击性。在阿斯伯格综合征患者中，报告的特征是多动和攻击性、学习困难和社交互动问题。语言发育迟缓的倒退和延迟在男孩中比在女孩中更为常见。
父母、家庭医生或儿科医生都应该非常注意孩子的行为以及他们的认知和语言发展。早期发现对于早期干预至关重要，我们的研究结果可以用于为父母和儿科医生制定早期识别 ASD 的培训计划。
