一种同时测定某些常用抗癫痫药物血药浓度的微量方法。
A micromethod for simultaneous estimation of blood levels of some commonly used antiepileptic drugs.
作者信息
Helmsing P J, van der Woude J, van Eupen O M
出版信息
Clin Chim Acta. 1978 Oct 16;89(2):301-9. doi: 10.1016/0009-8981(78)90329-7.
PMID:361295
Abstract
The analysis of serum samples for the antiepileptic drugs carbamazepine, phenobarbital and phenytoin by a simple extraction technique and chromatographic analysis by high-pressure liquid chromatography is described. The method is a micro one which correlates well with gas-liquid chromatographic procedures. Coefficients of variation are smaller than 3%.
摘要
描述了一种通过简单萃取技术分析血清样本中的抗癫痫药物卡马西平、苯巴比妥和苯妥英，并采用高压液相色谱进行色谱分析的方法。该方法是一种微量方法，与气液色谱法相关性良好。变异系数小于3%。
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