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心血管正电子发射断层扫描:在心血管疾病中的既定作用和新出现的作用

Cardiovascular positron emission tomography: established and emerging role in cardiovascular diseases.

作者信息

Bansal Amit, Ananthasubramaniam Karthikeyan

机构信息

UHS Wilson Medical Center, Johnson City, NY, USA.

Heart and Vascular Institute, Henry Ford West Bloomfield Hospital, 6777 W Maple, West Bloomfield, MI, 48322, USA.

出版信息

Heart Fail Rev. 2023 Mar;28(2):387-405. doi: 10.1007/s10741-022-10270-6. Epub 2022 Sep 21.

DOI:10.1007/s10741-022-10270-6
PMID:36129644
Abstract

Cardiac positron emission tomography (PET) imaging has established themselves firmly as excellent and reliable functional imaging modalities in assessment of the spectrum of coronary artery disease. With the explosion of technology advances and the dream of flow quantification now a reality, the value of PET is now well realized. Cardiac PET has proved itself as precise imaging modality that provides functional imaging of the heart in addition to anatomical imaging. It has established itself as one of the best available techniques for evaluation of myocardial viability. Hybrid PET/computed tomography provides simultaneous integration of coronary anatomy and function with myocardial perfusion and metabolism, thereby improving characterization of the dysfunctional area and chronic coronary artery disease. The availability of quantitative myocardial blood flow evaluation with PET provides additional prognostic information and increases diagnostic accuracy in the management of patients with coronary artery disease. Hybrid imaging seems to hold immense potential in optimizing management of cardiovascular diseases and furthering clinical research.

摘要

心脏正电子发射断层扫描(PET)成像已稳固确立其自身作为评估冠状动脉疾病谱的出色且可靠的功能成像方式。随着技术进步的迅猛发展以及血流定量如今成为现实,PET的价值现已得到充分认识。心脏PET已证明自身是一种精确的成像方式,除了解剖成像外,还能提供心脏的功能成像。它已确立自身为评估心肌存活的最佳可用技术之一。PET/计算机断层扫描混合成像可同时整合冠状动脉解剖结构与功能以及心肌灌注与代谢,从而改善对功能障碍区域和慢性冠状动脉疾病的特征描述。PET定量心肌血流评估的可用性提供了额外的预后信息,并提高了冠状动脉疾病患者管理中的诊断准确性。混合成像在优化心血管疾病管理和推进临床研究方面似乎具有巨大潜力。

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