Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal.
Faculdade de Medicina, Universidade de Coimbra, Coimbra, Portugal; Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Rev Port Cardiol (Engl Ed). 2020 Jan;39(1):37-46. doi: 10.1016/j.repc.2019.05.014. Epub 2020 Mar 4.
Cardiovascular disease is the leading cause of death worldwide and ischemic heart disease is the most frequent etiology, with high economic costs for both treatment and diagnosis. Over the past two decades, the assessment of patients with this disease has undergone various changes, with cardiac positron emission tomography (PET) emerging as a powerful and versatile imaging exam for diagnosis and risk stratification of these patients. This review aimed to assess the utility of this exam, particularly through quantification of myocardial blood flow and myocardial flow reserve in the diagnosis and risk stratification of coronary artery disease. Compared to other imaging methods, measurement of these parameters by cardiac PET provides a better characterization of coronary artery disease, with particular value in microvascular and balanced multivessel disease.
心血管疾病是全球范围内的主要致死原因，其中缺血性心脏病是最常见的病因，其治疗和诊断的经济成本都很高。在过去的二十年中，这种疾病的评估发生了各种变化，心脏正电子发射断层扫描（PET）作为一种强大而通用的成像检查手段，用于这些患者的诊断和风险分层。本综述旨在评估该检查的实用性，特别是通过量化心肌血流和心肌血流储备来诊断和分层冠状动脉疾病的风险。与其他成像方法相比，心脏 PET 测量这些参数可以更好地描述冠状动脉疾病，在微血管和平衡多血管疾病中具有特殊价值。
