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经皮内镜下椎间孔切开椎间盘切除术早期和中期不良预后的相关危险因素:单中心经验

Risk Factors Involved in the Early and Medium-Term Poor Outcomes of Percutaneous Endoscopic Transforaminal Discectomy: A Single-Center Experience.

作者信息

Wu Hui, Hu Shen, Liu Jiahao, He Dingwen, Chen Qi, Cheng Xigao

机构信息

Department of Orthopaedics, the Second Affiliated Hospital of Nanchang University, Nanchang city, Jiangxi Province, 330006, People's Republic of China.

出版信息

J Pain Res. 2022 Sep 15;15:2927-2938. doi: 10.2147/JPR.S380946. eCollection 2022.

Abstract

OBJECTIVE

To investigate the risk factors involved in the early and medium-term poor outcomes of percutaneous endoscopic transforaminal discectomy (PETD) treatment of lumbar disc herniation (LDH) at the L4-5 level.

METHODS

Between January 2015 and May 2020, we recruited 148 LDH patients at the L4-5 level who underwent PETD surgery. The patients were divided into Groups A and B, according to the surgical outcomes. Good and excellent outcomes were categorized into Group A, and generally good and poor outcomes were categorized into Group B. Clinical parameters (age, gender, symptom duration, hospital stay, operation time, blood loss, straight-leg raising (SLR), visual analog scale (VAS), Oswestry Disability Index (ODI) score and modified MacNab criteria) and radiologic parameters (foraminal height (FH), intervertebral height index (IHI), intervertebral angle (IVA), sagittal range of motion (sROM), and lumbar lordosis (LL)) were collected and analyzed using univariate and multiple logistic regression analyses.

RESULTS

At the 6-month follow-up post operation, univariate analysis revealed that the symptom duration, SLR, IHI, and sROM were strongly associated with poor outcomes. However, multiple logistic regression analysis demonstrated that prolonged symptom duration, large SLR angel, and large sROM were independent risk factors for poor outcomes. At the 2-year follow-up post operation, univariate analysis suggested that advanced age, prolonged symptom duration, large preoperative VAS score, small FH, small IHI, and large sROM were potential risk factors for poor outcomes. However, multiple logistic regression analysis demonstrated that prolonged symptom duration, small IHI, and large sROM were independent risk factors for poor outcomes.

CONCLUSION

Our study demonstrated that prolonged symptom duration, large SLR angel, and large sROM were independent risk factors for poor outcomes immediately following PETD at the L4-5 level. However, prolonged symptom duration, small IHI, and large sROM were independent risk factors for poor outcomes at medium-term post PETD at the L4-5 level.

摘要

目的

探讨经皮内镜下椎间孔入路椎间盘切除术(PETD)治疗L4-5节段腰椎间盘突出症(LDH)早期和中期预后不良的相关危险因素。

方法

2015年1月至2020年5月,我们招募了148例行PETD手术的L4-5节段LDH患者。根据手术结果将患者分为A组和B组。优良结果归入A组,一般良好和不良结果归入B组。收集临床参数(年龄、性别、症状持续时间、住院时间、手术时间、失血量、直腿抬高试验(SLR)、视觉模拟评分法(VAS)、Oswestry功能障碍指数(ODI)评分和改良MacNab标准)和影像学参数(椎间孔高度(FH)、椎间高度指数(IHI)、椎间角(IVA)、矢状面活动度(sROM)和腰椎前凸(LL)),并采用单因素和多因素logistic回归分析进行分析。

结果

术后6个月随访时,单因素分析显示症状持续时间、SLR、IHI和sROM与预后不良密切相关。然而,多因素logistic回归分析表明,症状持续时间延长、SLR角度大、sROM大是预后不良的独立危险因素。术后2年随访时,单因素分析提示高龄、症状持续时间延长、术前VAS评分高、FH小、IHI小、sROM大是预后不良的潜在危险因素。然而,多因素logistic回归分析表明,症状持续时间延长、IHI小、sROM大是预后不良的独立危险因素。

结论

我们的研究表明,症状持续时间延长、SLR角度大、sROM大是L4-5节段PETD术后立即出现预后不良的独立危险因素。然而,症状持续时间延长、IHI小、sROM大是L4-5节段PETD术后中期预后不良的独立危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37b6/9484800/260b6af1d610/JPR-15-2927-g0001.jpg

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