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血管内动脉瘤修复术后支架移植物位移力的快速准确计算

Fast and Accurate Computation of the Displacement Force of Stent Grafts after Endovascular Aneurysm Repair.

作者信息

Qing Ming, Liu Zhan, Zheng Tinghui

机构信息

Department of Applied Mechanics, Sichuan University, Chengdu 610065, China.

AVIC Chengdu Aircraft Industry (Group) Co., Ltd., Chengdu 610091, China.

出版信息

Bioengineering (Basel). 2022 Sep 6;9(9):447. doi: 10.3390/bioengineering9090447.

Abstract

Currently, the displacement force of stent grafts is generally obtained using computational fluid dynamics (CFD), which requires professional CFD knowledge to perform the correct simulation. This study proposes a fast, simple, and clinician-friendly approach to calculating the patient-specific displacement force after endovascular aneurysm repair (EVAR). Twenty patient-specific post-EVAR computed tomography angiography images were used to reconstruct the patient-specific three-dimensional models, then the displacement forces were calculated using CFD and the proposed approaches, respectively, and their numerical differences were compared and analyzed. Based on the derivation and simplification of the momentum theorem, the patient-specific displacement forces were obtained using the information of the patient-specific pressure, cross-sectional area, and angulation of the two stent graft ends, and the average relative error was no greater than 1.37% when compared to the displacement forces calculated by CFD. In addition, the linear regression analysis also showed good agreement between the displacement force values calculated by the new approach and CFD (R = 0.999). The proposed approach can quickly and accurately calculate the patient-specific displacement force on a stent graft and can therefore help clinicians quickly evaluate the post-EVAR displacement force.

摘要

目前,支架移植物的位移力通常使用计算流体动力学(CFD)来获取,这需要专业的CFD知识才能进行正确的模拟。本研究提出了一种快速、简单且对临床医生友好的方法,用于计算血管内动脉瘤修复(EVAR)后患者特异性的位移力。使用20例患者特异性的EVAR术后计算机断层扫描血管造影图像来重建患者特异性的三维模型,然后分别使用CFD和所提出的方法计算位移力,并对它们的数值差异进行比较和分析。基于动量定理的推导和简化,利用患者特异性压力、两个支架移植物末端的横截面积和角度信息获得患者特异性的位移力,与CFD计算的位移力相比,平均相对误差不大于1.37%。此外,线性回归分析还表明新方法计算的位移力值与CFD之间具有良好的一致性(R = 0.999)。所提出的方法可以快速准确地计算支架移植物上患者特异性的位移力,因此可以帮助临床医生快速评估EVAR后的位移力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7428/9495395/eac844ec3bc0/bioengineering-09-00447-g001.jpg

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