Bruminhent Jackrapong, Kaewsanga Yosapan, Jiraaumpornpat Werapoj, Arnuntasupakul Vanlapa, Suwatanapongched Thitiporn, Kiertiburanakul Sasisopin
Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Trop Med Infect Dis. 2022 Sep 10;7(9):238. doi: 10.3390/tropicalmed7090238.
A hospitel is a hotel that has been designated as an extension of the healthcare facilities during the COVID-19 pandemic in resource-limited settings. However, the clinical course and outcomes of patients with COVID-19 admitted to this unique type of facility have never been studied. We retrospectively reviewed the medical records of adult patients with COVID-19 who were admitted to a single hospitel in Bangkok, Thailand. Risk factors with respect to chest X-ray progression and clinical progression were analyzed using a logistic regression. A total of 514 patients were recruited, with a mean (standard deviation) age of 35.6 (13.4) years, and 58.6% were women. Patients were admitted after a median (interquartile range) of 3 (2−6) days of illness and were classified with mild (12.3%), moderate (86.6%), and severe (1.1%) conditions. Favipiravir and corticosteroids were prescribed in 26.3% and 14.9% of patients, respectively. Chest X-ray progression was found in 7.6% of patients, and hospital transfer occurred in 2.9%, with no deaths. Favipiravir use (odds ratio (OR) 3.3, 95% confidence interval (CI) 1.4−7.5, p = 0.005), nausea/vomiting after admission (OR 32.3, 95% CI 1.5−700.8, p = 0.03), and higher oxygen saturation on admission (OR 1.99; 95% CI 1.22−3.23, p = 0.005) were factors associated with chest X-ray progression. Additionally, an oxygen requirement on admission was an independent risk factor for hospital transfer (OR 904, 95% CI 113−7242, p < 0.001). In a setting where the hospitel has been proposed as an extension facility for patients with relatively non-severe COVID-19, most patients could achieve a favorable clinical outcome. However, patients who require oxygen supplementation should be closely monitored for disease progression and promptly transferred to a hospital if necessary.
在资源有限的环境中,“酒店医院”是指在新冠疫情期间被指定为医疗设施延伸的酒店。然而,入住这类特殊设施的新冠患者的临床病程和预后从未被研究过。我们回顾性分析了泰国曼谷一家“酒店医院”收治的成年新冠患者的病历。采用逻辑回归分析胸部X光进展和临床进展的危险因素。共招募了514例患者,平均(标准差)年龄为35.6(13.4)岁,58.6%为女性。患者在发病中位数(四分位间距)3(2 - 6)天后入院,病情分类为轻症(12.3%)、中症(86.6%)和重症(1.1%)。分别有26.3%和14.9%的患者使用了法匹拉韦和皮质类固醇。7.6%的患者出现胸部X光进展,2.9%的患者转院,无死亡病例。使用法匹拉韦(比值比(OR)3.3,95%置信区间(CI)1.4 - 7.5,p = 0.005)、入院后恶心/呕吐(OR 32.3,95% CI 1.5 - 700.8,p = 0.03)以及入院时较高的血氧饱和度(OR 1.99;95% CI 1.22 - 3.23,p = 0.005)是与胸部X光进展相关的因素。此外,入院时需要吸氧是转院的独立危险因素(OR 904,95% CI 113 - 7242,p < 0.001)。在将“酒店医院”作为相对非重症新冠患者延伸设施的情况下,大多数患者可取得良好的临床预后。然而,需要吸氧的患者应密切监测疾病进展,必要时及时转院。