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泰国医院中新冠肺炎患者的临床特征、治疗结果及费用:基于胸部X光检查结果的比较分析

Clinical characteristics, outcomes, and costs of COVID-19 patients in Thai hospitels: a comparative analysis based on chest X-ray findings.

作者信息

Sayabovorn Naruemit, Phisalprapa Pochamana, Srivanichakorn Weerachai, Chaisathaphol Thanet, Washirasaksiri Chaiwat, Sitasuwan Tullaya, Auesomwang Chonticha, Kositamongkol Chayanis, Nimitpunya Pongpol, Attachitwatin Teerapat, Chayakulkeeree Methee, Phoompoung Pakpoom, Nopmaneejumruslers Cherdchai, Taweemonkongsap Tawatchai, Vamvanij Visit, Tinmanee Rungsima

机构信息

Division of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

BMC Infect Dis. 2025 Jan 9;25(1):46. doi: 10.1186/s12879-025-10443-2.

DOI:10.1186/s12879-025-10443-2
PMID:39789466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11720629/
Abstract

BACKGROUND

"Hospitels" are hotels that have been specially converted to healthcare facilities. Their utilization emerged as a resource-optimization strategy during the peak of the COVID-19 pandemic in Thailand. This study evaluated the clinical characteristics, outcomes, and admission costs of asymptomatic and mild-to-moderate COVID-19 patients treated in these facilities.

METHODS

We conducted a retrospective analysis of adult COVID-19 patients who were admitted between July and October 2021 to two hospitels in Bangkok that were affiliated with Siriraj Hospital. Patient demographics, clinical data, vaccination status, treatment modalities, outcomes, and total costs were collected and analyzed via univariable and multivariable statistical methods.

RESULTS

Of the 1729 patients, 644 (37.2%) presented with abnormal baseline chest X-rays that could imply to moderate cases. These patients were older (49.2 vs. 42.2 years, P < 0.001), had greater body weights (68.1 vs. 64.7 kg, P < 0.001) and body mass indices (26.3 vs. 24.9 kg/m, P < 0.001), and more frequently presented comorbidities. They demonstrated an increased risk for severe COVID-19 (P < 0.001), lower full vaccination rates (P < 0.001), and higher hospital referral rates (P < 0.001). Symptomatology was largely comparable between patients with normal and abnormal baseline chest X-rays, with significant differences noted only for cough and fatigue. While the admission costs of both groups were similar, the total costs for referred patients were sixfold greater than those for discharged patients (70 545 vs. 12 010 Thai Baht, P < 0.001).

CONCLUSIONS

Compared with patients with normal baseline chest X-rays, COVID-19 patients with abnormal chest X-rays admitted to hospitels presented higher comorbidity rates, greater severe disease risk, and increased hospital referral rates. Referrals from the hospitels back to Siriraj Hospital substantially escalated the total costs. Vigilant monitoring of patients with initial abnormal chest X-rays in hospitels is crucial for efficient management and resource allocation.

摘要

背景

“医院式酒店”是指专门改造为医疗保健设施的酒店。在泰国新冠疫情高峰期,其利用成为一种资源优化策略。本研究评估了在这些设施中接受治疗的无症状和轻至中度新冠患者的临床特征、治疗结果及住院费用。

方法

我们对2021年7月至10月期间入住曼谷两家隶属于诗里拉吉医院的医院式酒店的成年新冠患者进行了回顾性分析。收集患者的人口统计学资料、临床数据、疫苗接种状况、治疗方式、治疗结果及总费用,并通过单变量和多变量统计方法进行分析。

结果

在1729例患者中,644例(37.2%)基线胸部X光片异常,提示为中度病例。这些患者年龄较大(49.2岁对42.2岁,P<0.001),体重(68.1千克对64.7千克,P<0.001)和体重指数(26.3千克/平方米对24.9千克/平方米,P<0.001)更高,且合并症更常见。他们发生重症新冠的风险增加(P<0.001),全程接种疫苗率较低(P<0.001),转院率较高(P<0.001)。基线胸部X光片正常和异常的患者症状大体相似,仅咳嗽和疲劳有显著差异。虽然两组的住院费用相似,但转院患者的总费用是出院患者的六倍(70545泰铢对12010泰铢,P<0.001)。

结论

与基线胸部X光片正常的患者相比,入住医院式酒店的胸部X光片异常的新冠患者合并症发生率更高,发生重症疾病的风险更大,转院率增加。从医院式酒店转回诗里拉吉医院大幅增加了总费用。对医院式酒店中初始胸部X光片异常的患者进行密切监测对于有效管理和资源分配至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a455/11720629/37ab526ee1c1/12879_2025_10443_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a455/11720629/f51c6770cdfb/12879_2025_10443_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a455/11720629/37ab526ee1c1/12879_2025_10443_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a455/11720629/f51c6770cdfb/12879_2025_10443_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a455/11720629/37ab526ee1c1/12879_2025_10443_Fig2_HTML.jpg

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