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氟化亚锡在乳牙和早期混合牙列中预防龋齿的有效性:一项系统评价。

Effectiveness of Silver Diamine Fluoride in Arresting Caries in Primary and Early Mixed Dentition: A Systematic Review.

作者信息

Hafiz Zain, Allam Rehab, Almazyad Bdoor, Bedaiwi Alya'a, Alotaibi Areej, Almubrad Alwateen

机构信息

Pediatric Dentistry and Orthodontics Department, College of Dentistry, King Saud University, Riyadh 12372, Saudi Arabia.

Intern, College of Dentistry, King Saud University, Riyadh 12372, Saudi Arabia.

出版信息

Children (Basel). 2022 Aug 26;9(9):1289. doi: 10.3390/children9091289.

DOI:10.3390/children9091289
PMID:36138602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9497160/
Abstract

Dental caries is a painful condition that could lead to nutritional problems which affects the overall health of the child, as well it is expensive to treat. The effectiveness of silver diamine fluoride (SDF) in primary and early mixed dentition is systematically reviewed in this study. This systematic review utilized the Preferred Reporting Items for Systematic reviews and Meta- Analysis statement (PRISMA, 2020). A literature search conducted using the common electronic databases (from 2010-2021). Based on the inclusion and exclusion criteria, ten randomized clinical trials (RCT) have met the inclusion criteria and were considered for the qualitative assessment. Critical appraisal of these studies was done. This systematic review found that using SDF is a successful and effective method in arresting dentin carious process in the primary teeth and first permanent molars in children. Additionally, when compared to the commonly used topical fluoride products and materials, SDF showed to have better cariostatic effect. However, these findings must be cautiously viewed since more research is required to support them.

摘要

龋齿是一种会引发疼痛的病症,可能导致营养问题,进而影响儿童的整体健康,而且治疗费用高昂。本研究对氟化亚锡(SDF)在乳牙列和早期混合牙列中的有效性进行了系统评价。本系统评价采用了系统评价和Meta分析的首选报告项目声明(PRISMA,2020)。使用常见电子数据库(2010 - 2021年)进行文献检索。根据纳入和排除标准,十项随机临床试验(RCT)符合纳入标准,并被纳入定性评估。对这些研究进行了严格评价。本系统评价发现,使用SDF是阻止儿童乳牙和第一恒磨牙牙本质龋病进程的一种成功且有效的方法。此外,与常用的局部用氟产品和材料相比,SDF显示出更好的抑龋效果。然而,由于需要更多研究来支持这些发现,因此必须谨慎看待这些结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d639/9497160/24f6b50a4caa/children-09-01289-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d639/9497160/dd526245b23d/children-09-01289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d639/9497160/24f6b50a4caa/children-09-01289-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d639/9497160/dd526245b23d/children-09-01289-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d639/9497160/24f6b50a4caa/children-09-01289-g002.jpg

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本文引用的文献

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J Dent Sci. 2022 Jan;17(1):300-307. doi: 10.1016/j.jds.2021.03.014. Epub 2021 Apr 10.
2
Caries arrest and lesion appearance using two different silver fluoride therapies on primary teeth with and without potassium iodide: 12-month results.两种不同的氟化银疗法对有/无碘化钾的乳牙龋齿抑制和病变外观的影响:12 个月的结果。
Clin Exp Dent Res. 2021 Aug;7(4):609-619. doi: 10.1002/cre2.367. Epub 2020 Dec 28.
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Arresting early childhood caries using silver and fluoride products - A randomised trial.
对38%氟化亚锡银的更广泛分析范围
Cureus. 2023 Aug 23;15(8):e44010. doi: 10.7759/cureus.44010. eCollection 2023 Aug.
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Inhibition of Demineralization of Dentin by Fluoride-Containing Hydrogel Desensitizers: An In Vitro Study.含氟水凝胶脱敏剂对牙本质脱矿的抑制作用:一项体外研究。
J Funct Biomater. 2022 Nov 16;13(4):246. doi: 10.3390/jfb13040246.
采用银和氟化物产品抑制幼儿龋齿——一项随机试验。
J Dent. 2020 Dec;103:103522. doi: 10.1016/j.jdent.2020.103522. Epub 2020 Nov 6.
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