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两种不同的氟化银疗法对有/无碘化钾的乳牙龋齿抑制和病变外观的影响:12 个月的结果。

Caries arrest and lesion appearance using two different silver fluoride therapies on primary teeth with and without potassium iodide: 12-month results.

机构信息

Faculty of Dentistry, University of Puthisastra, Phnom Penh, Cambodia.

出版信息

Clin Exp Dent Res. 2021 Aug;7(4):609-619. doi: 10.1002/cre2.367. Epub 2020 Dec 28.

Abstract

BACKGROUND

Globally, has been an increase in the use of silver fluoride products to arrest carious lesions and a variety of products are available.

OBJECTIVES

To examine differences in caries arrest and lesion colour of primary tooth carious lesions.

MATERIAL AND METHODS

A four-armed, parallel-design cluster-randomised controlled trial which investigated four protocols for caries arrest at 6m and 12m. Children in Group 1 and Group 2 received Rivastar Silver Diammine Fluoride (SDF), and children in Group 3 and Group 4 received a stabilised aqueous silver fluoride solution (AgF). Children in Group 2 and Group 4 received an additional application of KI immediately after the fluoride. Differences in caries arrest and lesion appearance were examined at 6m and 12m using two level logistic regression modelling.

RESULTS

The arrest rate varied by group membership; group 1 and group 3 had higher arrest rates (77.3% and 75.3% respectively) than group 2 and group 4 (65.4% and 51.2% respectively). The use of KI was also associated with lower odds of arrest (12m OR 0.25; CI 0.19, 0.34) and higher odds of avoiding black discolouration (12m OR 6.08; 2.36, 15.67).

CONCLUSIONS

Globally, has been an increase in the use of silver fluoride products to arrest carious lesions and a variety of products are available. This study demonstrated that both AgF and SDF can effectively arrest carious lesions on primary teeth. The use of KI is associated with poorer caries control but better aesthetic outcomes.

摘要

背景

全球范围内,使用银氟化物产品来阻止龋齿病变的情况有所增加,并且有多种产品可供选择。

目的

研究不同的银氟化物产品在阻止乳牙龋齿病变和病变颜色方面的效果差异。

材料和方法

这是一项四臂、平行设计的群组随机对照试验,研究了四种在 6 个月和 12 个月时阻止龋齿的方案。第 1 组和第 2 组的儿童使用 Rivastar 银氨氟化钾(SDF),第 3 组和第 4 组的儿童使用稳定的水性银氟化物溶液(AgF)。第 2 组和第 4 组的儿童在涂氟后立即使用碘化钾(KI)进行额外处理。使用二级逻辑回归模型,在 6 个月和 12 个月时检查龋齿抑制和病变外观的差异。

结果

不同组别的抑制率不同;第 1 组和第 3 组的抑制率较高(分别为 77.3%和 75.3%),而第 2 组和第 4 组的抑制率较低(分别为 65.4%和 51.2%)。KI 的使用也与较低的抑制率(12 个月 OR 0.25;CI 0.19, 0.34)和较高的避免黑色变色的几率(12 个月 OR 6.08;2.36, 15.67)相关。

结论

全球范围内,使用银氟化物产品来阻止龋齿病变的情况有所增加,并且有多种产品可供选择。本研究表明,AgF 和 SDF 都可以有效地阻止乳牙的龋齿病变。KI 的使用与较差的龋齿控制相关,但美学效果较好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a752/9632638/37b96a034c2e/CRE2-7-609-g001.jpg

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