Detti Beatrice, Bardoscia Lilia, Pisani Antonio Rosario, Cozzi Salvatore, Roghi Manuele, Mammucci Paolo, Sardaro Angela
Radiotherapy Unit, Azienda Ospedaliera-Universitaria Careggi, 50134 Florence, Italy.
Radiation Oncology Unit, S. Luca Hospital, Healthcare Company Tuscany Nord Ovest, 55100 Lucca, Italy.
Brain Sci. 2022 Sep 8;12(9):1209. doi: 10.3390/brainsci12091209.
Intracranial hemangiopericytomas are rare tumors, accounting for 1% of all central nervous system malignancies. This tumor is considered at high risk of local and also distant metastases. Surgical excision is the gold standard for treatment, but it is seldom curative by itself. Adjuvant radiotherapy is often recommended. We report an overview and update of the available literature on one such rare but aggressive mesenchymal tumor, using the case of a 46-year-old woman affected by hemangiopericytoma of the cavernous sinus surgically removed and treated with adjuvant radiotherapy at our institution. After seven years, the patient underwent a local recurrence and was treated with exeresis and Gamma Knife radiotherapy. Sixteen years after the initial diagnosis, she is still well with stable disease.
颅内血管外皮细胞瘤是罕见肿瘤,占所有中枢神经系统恶性肿瘤的1%。该肿瘤被认为具有局部及远处转移的高风险。手术切除是治疗的金标准,但单独手术很少能治愈。通常建议进行辅助放疗。我们报告了一种此类罕见但侵袭性间叶肿瘤的现有文献综述及更新情况,以一名46岁女性为例,她患有海绵窦血管外皮细胞瘤,在我们机构接受了手术切除及辅助放疗。七年后,患者出现局部复发,接受了切除及伽玛刀放疗。初始诊断16年后,她病情稳定,状况良好。