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低毫安CT透视引导下胰腺手术后经皮引流管置入:14年间133例连续患者的技术与临床结果

Low-Milliampere CT Fluoroscopy-Guided Percutaneous Drainage Placement after Pancreatic Surgery: Technical and Clinical Outcome in 133 Consecutive Patients during a 14-Year Period.

作者信息

Trumm Christoph G, Hackner Danilo, Badmann Katharina, Crispin Alexander, Forbrig Robert, Ozpeynirci Yigit, Kuppinger David, Pedersen Vera, Liebig Thomas, Stahl Robert

机构信息

Institute for Diagnostic and Interventional Neuroradiology, University Hospital, Ludwig-Maximilians-University (LMU), Marchioninistr. 15, 81377 Munich, Germany.

Department of General and Visceral Surgery, University Hospital Erlangen, Friedrich-Alexander-University (FAU) Erlangen-Nuremberg, Krankenhausstr. 12, 91054 Erlangen, Germany.

出版信息

Diagnostics (Basel). 2022 Sep 16;12(9):2243. doi: 10.3390/diagnostics12092243.

Abstract

(1) Purpose: To retrospectively assess the technical and clinical outcome of patients with symptomatic postoperative fluid collections after pancreatic surgery, treated with CT-guided drainage (CTD). (2) Methods: 133 eligible patients between 2004 and 2017 were included. We defined technical success as the sufficient drainage of the fluid collection(s) and the absence of peri-interventional complications (minor or major according to SIR criteria). Per definition, clinical success was characterized by normalization of specific blood parameters within 30 days after the intervention or a decrease by at least 50% without requiring additional surgical revision. C-reactive protein (CRP), Leukocytes, Interleukin-6, and Dose length product (DLP) for parts of the intervention were determined. (3) Results: 97.0% of 167 interventions were technically successful. Clinical success was achieved in 87.5% of CRP, in 78.4% of Leukocytes, and in 87.5% of Interleukin-6 assessments. The median of successful decrease was 6 days for CRP, 5 days for Leukocytes, and 2 days for Interleukin-6. No surgical revision was necessary in 93.2%. DLP was significantly lower in the second half of the observation period (total DLP: median 621.5 mGycm between 2011-2017 vs. median 944.5 mGycm between 2004-2010). (4) Conclusions: Technical success rate of CTD was very high and the clinical success rate was fair to good. Given an elderly and multimorbid patient cohort, CTD can have a temporizing effect in the postoperative period after pancreatic surgery. Reducing the radiation dose over time might reflect developments in CT technology and increased experience of interventional radiologists.

摘要

(1)目的:回顾性评估接受CT引导下引流(CTD)治疗的胰腺手术后出现有症状的术后积液患者的技术及临床疗效。(2)方法:纳入2004年至2017年间133例符合条件的患者。我们将技术成功定义为积液充分引流且无介入治疗期间并发症(根据SIR标准分为轻微或严重)。根据定义,临床成功的特征是干预后30天内特定血液参数恢复正常,或至少降低50%且无需额外手术修正。测定了干预部分的C反应蛋白(CRP)、白细胞、白细胞介素-6和剂量长度乘积(DLP)。(3)结果:167次干预中有97.0%技术成功。CRP评估中有87.5%取得临床成功,白细胞评估中有78.4%取得临床成功,白细胞介素-6评估中有87.5%取得临床成功。CRP成功下降的中位数为6天,白细胞为5天,白细胞介素-6为2天。93.2%的患者无需手术修正。观察期后半段的DLP显著更低(总DLP:2011 - 2017年中位数为621.5 mGycm,2004 - 2010年中位数为944.5 mGycm)。(4)结论:CTD的技术成功率非常高,临床成功率良好。鉴于患者群体为老年人且患有多种疾病,CTD在胰腺手术后的术后阶段可起到暂时缓解作用。随着时间推移辐射剂量降低可能反映了CT技术的发展以及介入放射科医生经验的增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c451/9498101/9a00da72c5d7/diagnostics-12-02243-g002.jpg

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