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雄性和雌性驯鹿()在萨哈(雅库特)的脂肪基因表达谱存在差异。

Differences in Adipose Gene Expression Profiles between Male and Female Even Reindeer () in Sakha (Yakutia).

机构信息

Natural Resources Institute Finland (Luke), 31600 Jokioinen, Finland.

NordGen-Nordic Genetic Resource Centre, 1432 Ås, Norway.

出版信息

Genes (Basel). 2022 Sep 13;13(9):1645. doi: 10.3390/genes13091645.

Abstract

Reindeer are native to harsh northern Eurasian environments which are characterized by long and cold winters, short summers, and limited pasture vegetation. Adipose tissues play a significant role in these animals by modulating energy metabolism, immunity, and reproduction. Here, we have investigated the transcriptome profiles of metacarpal, perirenal, and prescapular adipose tissues in Even reindeer and searched for genes that were differentially expressed in male and female individuals. A total of 15,551 genes were expressed, where the transcriptome profile of metacarpal adipose tissue was found to be distinct from that of perirenal and prescapular adipose tissues. Interestingly, 10 genes, including , which is known to have an important role in adaptation and speciation in reindeer, were always upregulated in all three tissues of male reindeer.

摘要

驯鹿原产于严酷的北欧亚环境,其特点是冬季漫长而寒冷,夏季短暂,牧场植被有限。脂肪组织在这些动物中起着重要的作用,调节能量代谢、免疫和繁殖。在这里,我们研究了驯鹿掌骨、肾周和肩胛前脂肪组织的转录组谱,并搜索了在雄性和雌性个体中差异表达的基因。共有 15551 个基因表达,其中掌骨脂肪组织的转录组谱与肾周和肩胛前脂肪组织明显不同。有趣的是,10 个基因,包括 ,它在驯鹿的适应和物种形成中起着重要作用,在雄性驯鹿的所有三种组织中总是上调。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c61d/9498357/f0fe0bdb3bb8/genes-13-01645-g001.jpg

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