Jakse G, Hofstädter F
Eur Urol. 1978;4(5):356-60. doi: 10.1159/000473993.
The red cell adherence test allows the disclosure of the blood group antigens incorporated on the surface of the urothelium. In the course of dedifferentiation the urothelium will lose its antigenicity. We applied this test on superfical bladder tumours (T1), carcinoma in situ and cytological specimens and observed a close correlation between the test results and the course of the disease, e.g. if the test was positive the recurrent tumour would be superficial and vice versa. As a rule the negative results revealed atypical hyperplasia and carcinoma in situ as areas of potentially malignant and invasive tumours. With the application of the red cell adherence test to cytological preparations we can probably improve the accuracy of the cytological examination in cases of transitional cancer of low malignancy.
红细胞黏附试验可揭示尿路上皮表面所包含的血型抗原。在去分化过程中，尿路上皮会丧失其抗原性。我们将此试验应用于浅表性膀胱肿瘤（T1期）、原位癌及细胞学标本，观察到试验结果与疾病进程密切相关，例如，如果试验呈阳性，复发肿瘤将为浅表性，反之亦然。通常，阴性结果显示非典型增生和原位癌为潜在恶性和浸润性肿瘤区域。通过将红细胞黏附试验应用于细胞学标本，我们可能提高低恶性度移行细胞癌病例细胞学检查的准确性。
