Genus Seeds: A Review on Phytochemical Screening and Pharmacological Properties.

Traditionally, species are widely used in traditional medicine, human food, and animal feed. Recently, special attention has been dedicated to seeds as source of health-promoting phytochemicals. This review provides a summary of recent research on the seed phytochemistry, bioactivity, dietary importance, and toxicity by screening the major online scientific database sources and papers published in recent decades by Elsevier, Springer, and John Wiley. The search was conducted covering the period from January 1964 to July 2022. Phytochemically, polyphenols, glucosinolates, and their degradation products were the predominant secondary metabolites in seeds. Different extracts and their purified constituents from seeds of species have been found to possess a wide range of biological properties including antioxidant, anticancer, antimicrobial, anti-inflammatory, antidiabetic, and neuroprotective activities. These valuable functional properties of seeds are related to their richness in active compounds responsible for the prevention and treatment of various chronic diseases such as obesity, diabetes, cancer, and COVID-19. Currently, the potential properties of seeds and their components are the main focus of research, but their toxicity and health risks must also be accounted for.