Department of Pharmacy, University of Science and Technology Chittagong, Chattogram, Bangladesh.
Molecular Modeling Drug-design and Discovery Laboratory, Pharmacology Research Division, BCSIR Laboratories Chattogram, Bangladesh Council of Scientific and Industrial Research, Chattogram, Bangladesh.
Mini Rev Med Chem. 2021;21(16):2399-2417. doi: 10.2174/1389557521666210111150036.
Brassica oleracea var. capitata f. alba (white cabbage) is a cruciferous vegetable used as a vegetable and traditional medicine all over the world. Different preparation from several parts of the plant- roots, shoots, leaves, and the whole plant are used to treat a wide range of diseases, including diabetes, cancer, gastric, inflammation, hypertension, hypercholesterolemia, bacterial, oxidation, and obesity.
The aim of the current review is to evaluate the botany, distribution, traditional uses, phytochemistry, and pharmacological activities of B. oleracea var. capitata. Moreover, this review will guide to fill the existing gaps in information and highlight additional research prospects in the field of phytochemistry and pharmacology.
Various resources, including research papers, review papers, books, and reports, were collected to obtain overall information on Brassica oleracea var. capitata, which were obtained by an online search of worldwide-accepted scientific databases. Phytochemical constituents' structures were drawn by ChemDraw software.
About 72 isolated phytochemical compounds of B. oleracea var. capitata have been collected from different articles, which included different types of compounds such as alkaloids, flavonoids, organic acids, glucosinolates, steroids, hydrocarbons, etc. Crude extracts and phytoconstituents of B. oleracea var. capitata have various pharmacological effects, including antidiabetic, anticancer, antihypertensive, anticholesterolemic, antioxidant, anti-inflammatory, antibacterial, anti-obesity, anticoagulant, and hepatoprotective. We have enlisted all these pharmacological data along with all the phytochemical constituents of Brassica oleracea var. capitata.
The study was focused on the traditional uses, pharmacological activities, and phytochemistry of Brassica oleracea var. capitata, and the findings indicated that B. oleracea var. capitata is an important medicinal plant that shows several pharmacological effects. We hope our review of this plant will provide more basic and useful information and fill some research gaps for further investigation and drug design. Although we found some important traditional uses and pharmacological activities of Brassica oleracea var. capitata, there is insufficient work in the field of phytochemical activities.
结球甘蓝（白菜）是一种十字花科蔬菜，在世界各地被用作蔬菜和传统药物。植物的不同部位——根、茎、叶和整株植物都被用于治疗各种疾病，包括糖尿病、癌症、胃病、炎症、高血压、高胆固醇血症、细菌、氧化和肥胖。
本综述的目的是评估结球甘蓝的植物学、分布、传统用途、植物化学和药理学活性。此外，本综述将指导填补信息空白，并强调植物化学和药理学领域的额外研究前景。
通过在线搜索全球公认的科学数据库，收集了包括研究论文、评论文章、书籍和报告在内的各种资源，以获取有关结球甘蓝的全面信息。植物化学物质的结构用 ChemDraw 软件绘制。
从不同的文章中收集了约 72 种结球甘蓝的分离植物化学物质，其中包括生物碱、类黄酮、有机酸、硫代葡萄糖苷、甾体、烃等不同类型的化合物。结球甘蓝的粗提取物和植物成分具有多种药理作用，包括抗糖尿病、抗癌、降压、降胆固醇、抗氧化、抗炎、抗菌、抗肥胖、抗凝和保肝。我们列出了所有这些药理数据以及结球甘蓝的所有植物化学成分。
本研究重点关注结球甘蓝的传统用途、药理活性和植物化学，研究结果表明，结球甘蓝是一种重要的药用植物，具有多种药理作用。我们希望对这种植物的综述将提供更多的基础和有用信息，并填补一些研究空白，以进一步进行研究和药物设计。尽管我们发现了结球甘蓝的一些重要传统用途和药理活性，但在植物化学活性领域的工作还不够。
