Uematsu Y, Iwamoto M, Kuriyama T
No Shinkei Geka. 1987 Apr;15(4):435-40.
Here reported is a case of multiple septic intracranial aneurysms which were successfully treated with surgical and conservative therapy. A 44-year-old man was admitted to our hospital because of headache, vomiting and visual disturbance. He had had a fever and had been under treatment for a respiratory tract infection during the preceding 3 months. Physical examination on admission revealed pansystolic heart murmur over the cardiac apex. Neurological examination revealed neck stiffness, papilledema and right homonymous hemianopsia. Laboratory data showed the presence of inflammatory process. A CT scan showed a high density area in the left occipital region, and vertebral angiography showed a saccular aneurysm on a distal branch of the left occipitotemporal artery. Fourteen days after admission, the operation of clipping the neck of the aneurysmal artery was performed and the hematoma evacuated to lower the increased intracranial pressure. He had been well after the operation until 3 weeks later when a follow-up angiography showed a new unruptured aneurysm on a distal branch of the right middle cerebral artery with a relapse of the infection. Then, he was treated with appropriate antibiotics and antifibrinolytic agents. A repeated angiography 1 month later showed resolution of the aneurysm. The mechanism of resolution of septic aneurysm and its treatment are discussed.
本文报告一例多发性感染性颅内动脉瘤患者,经手术及保守治疗成功治愈。一名44岁男性因头痛、呕吐及视力障碍入院。在之前3个月里,他一直发热并接受呼吸道感染治疗。入院时体格检查发现心尖部全收缩期心脏杂音。神经系统检查发现颈部强直、视乳头水肿及右侧同向性偏盲。实验室检查结果显示存在炎症过程。CT扫描显示左枕叶区域有高密度区,椎动脉血管造影显示左枕颞动脉远端分支有一个囊状动脉瘤。入院14天后,对动脉瘤动脉颈部进行夹闭手术,并清除血肿以降低颅内压升高。术后他恢复良好,直到3周后随访血管造影显示右侧大脑中动脉远端分支出现一个新的未破裂动脉瘤,且感染复发。随后,他接受了适当的抗生素和抗纤维蛋白溶解剂治疗。1个月后重复血管造影显示动脉瘤消退。文中讨论了感染性动脉瘤消退的机制及其治疗方法。