Hospital Veterinario, Universidad del Tolima, Calle 20 Sur # 23A-160 Barrio Miramar, Ibagué 730010, Tolima, Colombia.
Grupo de Investigación en Medicina y Cirugía de Pequeños Animales, Facultad de Medicina Veterinaria y Zootecnia, Universidad del Tolima, Calle 20 Sur # 23A-160 Barrio Miramar, Ibagué 730010, Tolima, Colombia.
Viruses. 2022 Sep 1;14(9):1947. doi: 10.3390/v14091947.
Canine distemper virus (CDV) is the etiological agent of a highly prevalent viral infectious disease of domestic and wild carnivores. This virus poses a conservation threat to endangered species worldwide due to its ability to jump between multiple species and produce a disease, which is most often fatal. Although CDV infection has been regularly diagnosed in Colombian wildlife, to date the molecular identity of circulating CDV lineages is currently unknown. Our aim was to evaluate the presence and phylogenetic characterization of CDV detected in samples from naturally infected from Colombia. We sequenced for the first time the CDV infecting wildlife in Colombia and demonstrated the presence of South America/North America-4 Lineage with a higher relationship to sequences previously reported from domestic and wild fauna belonging to the United States of America. Our results are crucial for the understanding of the interspecies transmission of CDV in the domestic/wild interface and for the prevention and control of such an important multi-host pathogen.
犬瘟热病毒（CDV）是一种高度流行的病毒传染病的病原体，涉及家养和野生食肉动物。由于该病毒能够在多种物种之间跳跃并产生疾病，而且这种疾病通常是致命的，因此它对全球濒危物种构成了保护威胁。尽管 CDV 感染已在哥伦比亚野生动物中定期诊断出来，但迄今为止，循环 CDV 谱系的分子身份目前尚不清楚。我们的目的是评估在来自哥伦比亚自然感染的样本中检测到的 CDV 的存在和系统发育特征。我们首次对感染哥伦比亚野生动物的 CDV 进行了测序，并证明存在南美洲/北美洲-4 谱系，与之前从属于美利坚合众国的家养和野生动物中报告的序列关系更为密切。我们的研究结果对于理解 CDV 在家养/野生界面中的种间传播以及预防和控制这种重要的多宿主病原体至关重要。
