AlGhobaishi Abdullah, Mousa Ahmed Hafez, Alshaltoni Reham Salama, Mohsen Amani Sail, Baothman Abdullah, Adem Hanan, Eisa Yasir, Amin Abeer, Edrees Burhan
Department of Pediatrics, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
Department of Pediatrics, Saudi German Hospital, Jeddah, Saudi Arabia.
Ann Med Surg (Lond). 2022 Sep 1;81:104541. doi: 10.1016/j.amsu.2022.104541. eCollection 2022 Sep.
Lupus nephritis is particularly a very concerning occurrence due to the susceptibility for potential renal damage and ultimately renal failure. Cardiac involvement was present as well in the form of pericarditis. Our study reports a case of lupus nephritis that has had a very severe course of fluctuations between relapses and improvements which constantly necessitated an MDT interference at various points.
We report a case of a 13-year-old female patient who presented with a 5-day history of fever, dizziness, joint pain, menorrhagia, convulsions, and visual disturbances. Essential diagnostic tests took place and a diagnosis of lupus nephritis was confirmed.
In conclusion we found that a combination of various treatment modalities and flexibility in decision making in response to changes in the clinical course are vital to treatment success. Utilization of plasma exchange which resulted in an enormous drop in the percentage of fragmented red blood cells (RBCs) from 9.8% to 1.8%.
狼疮性肾炎尤其令人担忧，因为它有导致潜在肾损伤并最终发展为肾衰竭的风险。同时还存在以心包炎形式出现的心脏受累情况。我们的研究报告了一例狼疮性肾炎病例，其病情在复发和好转之间波动剧烈，在不同阶段都需要多学科团队（MDT）的干预。
我们报告一例13岁女性患者，有5天发热、头晕、关节疼痛、月经过多、抽搐和视觉障碍病史。进行了必要的诊断检查，确诊为狼疮性肾炎。
总之，我们发现多种治疗方式相结合以及根据临床病程变化灵活决策对治疗成功至关重要。采用血浆置换后，破碎红细胞（RBC）百分比从9.8%大幅降至1.8%。
